PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8254739-4 1994 We show by in situ hybridization of mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate (TPA) that VL30 expression is induced in epidermal keratinocytes but not in dermal fibroblasts. Tetradecanoylphorbol Acetate 60-96 RIKEN cDNA A130040M12 gene Mus musculus 108-112 8254739-4 1994 We show by in situ hybridization of mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate (TPA) that VL30 expression is induced in epidermal keratinocytes but not in dermal fibroblasts. Tetradecanoylphorbol Acetate 98-101 RIKEN cDNA A130040M12 gene Mus musculus 108-112 8254739-5 1994 Transient transfections of reporter gene plasmids together with in vitro binding analysis indicate that TPA-induced VL30 transcription specific for keratinocytes is mediated by two cooperating sequence motifs in juxtaposed position. Tetradecanoylphorbol Acetate 104-107 RIKEN cDNA A130040M12 gene Mus musculus 116-120 1722214-0 1991 Identification of protein-binding sequences mediating constitutive and 12-O-tetradecanoylphorbol-13-acetate-induced VL30 transcription in cultured mouse and human keratinocytes. Tetradecanoylphorbol Acetate 71-107 RIKEN cDNA A130040M12 gene Mus musculus 116-120 1722214-1 1991 A retrovirus-like 30S (VL30) gene induced in mouse epidermis after a single application of 12-O-tetradecanoylphorbol-13-acetate (TPA) was used as a model gene to define mechanisms of transcriptional regulation in keratinocytes. Tetradecanoylphorbol Acetate 91-127 RIKEN cDNA A130040M12 gene Mus musculus 23-27 1722214-1 1991 A retrovirus-like 30S (VL30) gene induced in mouse epidermis after a single application of 12-O-tetradecanoylphorbol-13-acetate (TPA) was used as a model gene to define mechanisms of transcriptional regulation in keratinocytes. Tetradecanoylphorbol Acetate 129-132 RIKEN cDNA A130040M12 gene Mus musculus 23-27 1722214-3 1991 Deletion mapping of the long terminal repeat region and linking short sequences to a heterologous promoter made it possible to identify a 28-base pair VL30 TPA-responsive element. Tetradecanoylphorbol Acetate 156-159 RIKEN cDNA A130040M12 gene Mus musculus 151-155 1722214-4 1991 VL30 TPA-responsive element mediated both basal and TPA-induced transcription in the mouse keratinocyte cell line Balb/MK and in normal human keratinocytes. Tetradecanoylphorbol Acetate 5-8 RIKEN cDNA A130040M12 gene Mus musculus 0-4 1722214-4 1991 VL30 TPA-responsive element mediated both basal and TPA-induced transcription in the mouse keratinocyte cell line Balb/MK and in normal human keratinocytes. Tetradecanoylphorbol Acetate 52-55 RIKEN cDNA A130040M12 gene Mus musculus 0-4 1722214-5 1991 Gel-retardation and transient transfection experiments indicated that two nuclear factors (VLX and VLY) bind independently to the VL30 TPA-responsive element in juxtaposed positions and that the binding sites collaborate functionally in constitutive and TPA-induced transcription. Tetradecanoylphorbol Acetate 135-138 RIKEN cDNA A130040M12 gene Mus musculus 130-134 1722214-5 1991 Gel-retardation and transient transfection experiments indicated that two nuclear factors (VLX and VLY) bind independently to the VL30 TPA-responsive element in juxtaposed positions and that the binding sites collaborate functionally in constitutive and TPA-induced transcription. Tetradecanoylphorbol Acetate 254-257 RIKEN cDNA A130040M12 gene Mus musculus 130-134 2105842-4 1990 Immunohistochemistry and time-kinetic studies on mRNA levels in mouse epidermis showed that the increase in MT and VL30 RNAs coincide in time with a TPA-induced transient block in basal cell proliferation (3-12 h after TPA treatment). Tetradecanoylphorbol Acetate 149-152 RIKEN cDNA A130040M12 gene Mus musculus 115-119 2105842-4 1990 Immunohistochemistry and time-kinetic studies on mRNA levels in mouse epidermis showed that the increase in MT and VL30 RNAs coincide in time with a TPA-induced transient block in basal cell proliferation (3-12 h after TPA treatment). Tetradecanoylphorbol Acetate 219-222 RIKEN cDNA A130040M12 gene Mus musculus 115-119 2105842-8 1990 VL30 and MT mRNA levels were not found to be elevated in epidermal tumors whereas the mRNA level corresponding to glyceraldehyde-3-phosphate dehydrogenase was elevated in tumors and induced by TPA with time-kinetics that correlate with a TPA-induced hyperproliferation. Tetradecanoylphorbol Acetate 193-196 RIKEN cDNA A130040M12 gene Mus musculus 0-4 3007488-2 1986 Tumor-promoting phorbol esters (e.g. 12-O-tetradecanoyl phorbol acetate (TPA] increased the level of VL30 expression. Tetradecanoylphorbol Acetate 37-71 RIKEN cDNA A130040M12 gene Mus musculus 101-105 3007488-2 1986 Tumor-promoting phorbol esters (e.g. 12-O-tetradecanoyl phorbol acetate (TPA] increased the level of VL30 expression. Tetradecanoylphorbol Acetate 73-76 RIKEN cDNA A130040M12 gene Mus musculus 101-105 3007488-3 1986 Stimulation with either TPA or EGF produced a similar time course of VL30 expression. Tetradecanoylphorbol Acetate 24-27 RIKEN cDNA A130040M12 gene Mus musculus 69-73 3007488-4 1986 TPA induced VL30 expression in the EGF-receptorless NR6 cell line, indicating that neither EGF ligand-receptor binding nor phosphorylation of the EGF receptor was required for induction of VL30 expression. Tetradecanoylphorbol Acetate 0-3 RIKEN cDNA A130040M12 gene Mus musculus 12-16