PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19376210-3 2009 Treatment of K562 chronic myelogenous leukemia cells with phorbol-12-myristate-13-acetate (PMA) induces megakaryocytic differentiation and Rac2 gene transcription following a lag of 6-12 h. Promoter/luciferase reporter gene assays reveal that a 135 bp cis-element located between -4223 and -4008 bp upstream of the Rac2 transcription start site is necessary and sufficient for PMA-induced gene expression. Tetradecanoylphorbol Acetate 58-89 Rac family small GTPase 2 Homo sapiens 139-143 31071452-6 2019 Cell lines transfected with RAC2 [N92 T] displayed characteristics of active GTP-bound RAC2 including enhanced NADPH oxidase-derived superoxide production both at rest and in response to PMA. Tetradecanoylphorbol Acetate 187-190 Rac family small GTPase 2 Homo sapiens 28-32 31071452-6 2019 Cell lines transfected with RAC2 [N92 T] displayed characteristics of active GTP-bound RAC2 including enhanced NADPH oxidase-derived superoxide production both at rest and in response to PMA. Tetradecanoylphorbol Acetate 187-190 Rac family small GTPase 2 Homo sapiens 87-91 19376210-3 2009 Treatment of K562 chronic myelogenous leukemia cells with phorbol-12-myristate-13-acetate (PMA) induces megakaryocytic differentiation and Rac2 gene transcription following a lag of 6-12 h. Promoter/luciferase reporter gene assays reveal that a 135 bp cis-element located between -4223 and -4008 bp upstream of the Rac2 transcription start site is necessary and sufficient for PMA-induced gene expression. Tetradecanoylphorbol Acetate 58-89 Rac family small GTPase 2 Homo sapiens 315-319 19376210-3 2009 Treatment of K562 chronic myelogenous leukemia cells with phorbol-12-myristate-13-acetate (PMA) induces megakaryocytic differentiation and Rac2 gene transcription following a lag of 6-12 h. Promoter/luciferase reporter gene assays reveal that a 135 bp cis-element located between -4223 and -4008 bp upstream of the Rac2 transcription start site is necessary and sufficient for PMA-induced gene expression. Tetradecanoylphorbol Acetate 91-94 Rac family small GTPase 2 Homo sapiens 139-143 19376210-3 2009 Treatment of K562 chronic myelogenous leukemia cells with phorbol-12-myristate-13-acetate (PMA) induces megakaryocytic differentiation and Rac2 gene transcription following a lag of 6-12 h. Promoter/luciferase reporter gene assays reveal that a 135 bp cis-element located between -4223 and -4008 bp upstream of the Rac2 transcription start site is necessary and sufficient for PMA-induced gene expression. Tetradecanoylphorbol Acetate 91-94 Rac family small GTPase 2 Homo sapiens 315-319 12594296-7 2003 In eosinophils stimulated with PMA, a pronounced shift of cytosolic Rac to p22(phox)-positive plasma membrane was observed by confocal microscopy, whereas neutrophils directed Rac2 mainly to intracellular sites coexpressing p22(phox). Tetradecanoylphorbol Acetate 31-34 Rac family small GTPase 2 Homo sapiens 176-180 10540223-10 1999 In subcellular fractions, Rac2 was found to translocate, along with p47phox and p67phox, from cytosol to plasma membrane-associated fractions following phorbol myristate acetate stimulation, while RhoGDI remained within cytosolic fractions. Tetradecanoylphorbol Acetate 152-177 Rac family small GTPase 2 Homo sapiens 26-30 8645270-3 1996 However, when the agonist was concanavalin A (ConA) or phorbol 12-myristate 13-acetate (PMA), rac 1 and rac 2, but not the p190 GAP, were translocated. Tetradecanoylphorbol Acetate 55-86 Rac family small GTPase 2 Homo sapiens 104-109 8645270-3 1996 However, when the agonist was concanavalin A (ConA) or phorbol 12-myristate 13-acetate (PMA), rac 1 and rac 2, but not the p190 GAP, were translocated. Tetradecanoylphorbol Acetate 88-91 Rac family small GTPase 2 Homo sapiens 104-109 8141770-3 1994 Activation of superoxide production by phorbol 12-myristate 13-acetate or formylmethionyl-leucyl-phenylalanine in whole cells, and by SDS in the cell-free assay, led to the dissociation of some of the p21rac2 from rhoGDI and its movement to the plasma membrane together with p47phox and p67phox. Tetradecanoylphorbol Acetate 39-70 Rac family small GTPase 2 Homo sapiens 201-208 7475908-7 1995 For the expression of Gi2 alpha and beta subunits, chronic TPA-treatment was required although Rac2, a low M(r) GTP-binding protein, was expressed abundantly by only 30 min-TPA-treatment followed by 3 day-culture. Tetradecanoylphorbol Acetate 173-176 Rac family small GTPase 2 Homo sapiens 95-99