PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11169972-5	2001	p70s6K, an important kinase involved in the regulation of protein synthesis and cell-cycle progression, has been reported to be activated through a PKC-dependent pathway (TPA-activatable) in addition to a PI3K-dependent pathway.	Tetradecanoylphorbol Acetate	171-174	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	0-6	
25027711-6	2014	TPA-induced phosphorylation of Akt, S6 kinase (S6K), and eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) in mouse skin was lower in the curcumin group than in the control group.	Tetradecanoylphorbol Acetate	0-3	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	36-45	
25027711-6	2014	TPA-induced phosphorylation of Akt, S6 kinase (S6K), and eukaryotic translation initiation factor 4E-binding protein 1 (4EBP1) in mouse skin was lower in the curcumin group than in the control group.	Tetradecanoylphorbol Acetate	0-3	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	47-50	
11169972-6	2001	Here, we demonstrate for the first time that TPA-stimulated MAPK activation is essential for the phosphorylation of several key residues involved in the activation of p70s6K, namely, thr389, thr421, and ser424.	Tetradecanoylphorbol Acetate	45-48	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	167-173	
10753872-3	2000	It is further shown that FTI inhibits p70s6k activation in response to serum, phorbol myristate acetate, and increased amino acid levels.	Tetradecanoylphorbol Acetate	78-103	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	38-44	
10851233-4	2000	The zinc-induced activation of p70S6k was partially inhibited by down-regulation of phorbol 12-myristate 13-acetate-responsive protein kinase C (PKC) by chronic treatment with phorbol 12-myristate 13-acetate, but this was not significant.	Tetradecanoylphorbol Acetate	84-115	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	31-37	
10851233-4	2000	The zinc-induced activation of p70S6k was partially inhibited by down-regulation of phorbol 12-myristate 13-acetate-responsive protein kinase C (PKC) by chronic treatment with phorbol 12-myristate 13-acetate, but this was not significant.	Tetradecanoylphorbol Acetate	176-207	ribosomal protein S6 kinase, polypeptide 1	Mus musculus	31-37