PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18787026-4 2009 We demonstrate that activation of the PKA and PKC pathways, by a cAMP analog dibutyryl (Bu)2cAMP [(Bu)2cAMP] and phorbol 12-myristate 13-acetate (PMA), respectively, markedly decreased DAX-1 expression, an event that was inversely correlated with StAR protein, StAR mRNA, and progesterone levels. Tetradecanoylphorbol Acetate 113-144 steroidogenic acute regulatory protein Mus musculus 247-251 19282384-3 2009 In the present study, we demonstrate that activation of the PKC pathway, by phorbol 12-myristate 13-acetate (PMA), was capable of potentiating dibutyryl cAMP [(Bu)(2)cAMP]-stimulated StAR expression, StAR phosphorylation, and progesterone synthesis in both mouse Leydig (MA-10) and granulosa (KK-1) tumor cells. Tetradecanoylphorbol Acetate 76-107 steroidogenic acute regulatory protein Mus musculus 183-187 19282384-3 2009 In the present study, we demonstrate that activation of the PKC pathway, by phorbol 12-myristate 13-acetate (PMA), was capable of potentiating dibutyryl cAMP [(Bu)(2)cAMP]-stimulated StAR expression, StAR phosphorylation, and progesterone synthesis in both mouse Leydig (MA-10) and granulosa (KK-1) tumor cells. Tetradecanoylphorbol Acetate 76-107 steroidogenic acute regulatory protein Mus musculus 200-204 19282384-3 2009 In the present study, we demonstrate that activation of the PKC pathway, by phorbol 12-myristate 13-acetate (PMA), was capable of potentiating dibutyryl cAMP [(Bu)(2)cAMP]-stimulated StAR expression, StAR phosphorylation, and progesterone synthesis in both mouse Leydig (MA-10) and granulosa (KK-1) tumor cells. Tetradecanoylphorbol Acetate 109-112 steroidogenic acute regulatory protein Mus musculus 183-187 19282384-3 2009 In the present study, we demonstrate that activation of the PKC pathway, by phorbol 12-myristate 13-acetate (PMA), was capable of potentiating dibutyryl cAMP [(Bu)(2)cAMP]-stimulated StAR expression, StAR phosphorylation, and progesterone synthesis in both mouse Leydig (MA-10) and granulosa (KK-1) tumor cells. Tetradecanoylphorbol Acetate 109-112 steroidogenic acute regulatory protein Mus musculus 200-204 18787026-4 2009 We demonstrate that activation of the PKA and PKC pathways, by a cAMP analog dibutyryl (Bu)2cAMP [(Bu)2cAMP] and phorbol 12-myristate 13-acetate (PMA), respectively, markedly decreased DAX-1 expression, an event that was inversely correlated with StAR protein, StAR mRNA, and progesterone levels. Tetradecanoylphorbol Acetate 113-144 steroidogenic acute regulatory protein Mus musculus 261-265 18787026-4 2009 We demonstrate that activation of the PKA and PKC pathways, by a cAMP analog dibutyryl (Bu)2cAMP [(Bu)2cAMP] and phorbol 12-myristate 13-acetate (PMA), respectively, markedly decreased DAX-1 expression, an event that was inversely correlated with StAR protein, StAR mRNA, and progesterone levels. Tetradecanoylphorbol Acetate 146-149 steroidogenic acute regulatory protein Mus musculus 247-251 18787026-4 2009 We demonstrate that activation of the PKA and PKC pathways, by a cAMP analog dibutyryl (Bu)2cAMP [(Bu)2cAMP] and phorbol 12-myristate 13-acetate (PMA), respectively, markedly decreased DAX-1 expression, an event that was inversely correlated with StAR protein, StAR mRNA, and progesterone levels. Tetradecanoylphorbol Acetate 146-149 steroidogenic acute regulatory protein Mus musculus 261-265 18755854-3 2008 MA-10 mouse Leydig tumor cells treated with an activator of PRKCC, phorbol 12-myristate 13-acetate (PMA), demonstrated increases in the expression of the STAR and CYP11A1 proteins and progesterone synthesis, which coincided with the expression and phosphorylation of JUN (P-JUN). Tetradecanoylphorbol Acetate 67-98 steroidogenic acute regulatory protein Mus musculus 154-158 18755854-3 2008 MA-10 mouse Leydig tumor cells treated with an activator of PRKCC, phorbol 12-myristate 13-acetate (PMA), demonstrated increases in the expression of the STAR and CYP11A1 proteins and progesterone synthesis, which coincided with the expression and phosphorylation of JUN (P-JUN). Tetradecanoylphorbol Acetate 100-103 steroidogenic acute regulatory protein Mus musculus 154-158 17400803-6 2007 Inhibition of ERK1/2 activity by U0126 decreased PMA-treated StAR expression but increased dbcAMP/hCG-mediated StAR and P-StAR; however, progesterone levels were attenuated. Tetradecanoylphorbol Acetate 49-52 steroidogenic acute regulatory protein Mus musculus 61-65 15814901-3 2005 These observations were corroborated in MA-10 and mLTC-1 Leydig tumor cell lines, in which activation of PKC by phorbol-12-myristate-13-acetate (PMA, 10 nM) increased CREB phosphorylation and total StAR (tot-StAR) protein expression. Tetradecanoylphorbol Acetate 112-143 steroidogenic acute regulatory protein Mus musculus 198-202 15814901-3 2005 These observations were corroborated in MA-10 and mLTC-1 Leydig tumor cell lines, in which activation of PKC by phorbol-12-myristate-13-acetate (PMA, 10 nM) increased CREB phosphorylation and total StAR (tot-StAR) protein expression. Tetradecanoylphorbol Acetate 112-143 steroidogenic acute regulatory protein Mus musculus 208-212