PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10329111-2 1999 LPS pretreatment inhibits subsequent LPS-stimulated MAPK activation and TNF release and both were reversed if macrophages were treated with phorbol myristate acetate (PMA) before LPS stimulation. Tetradecanoylphorbol Acetate 140-165 toll-like receptor 4 Mus musculus 0-3 15996188-5 2005 Furthermore, the percentages of the T cells isolated from the spleens of DBA/2 mice exposed to both mercury and LPS that produced pro-inflammatory cytokines were markedly increased by in vitro stimulation with phorbol myristate acetate (PMA) and ionomycin, which was not the case for splenic T cells isolated from mice receiving mercuric chloride, LPS or saline alone. Tetradecanoylphorbol Acetate 210-235 toll-like receptor 4 Mus musculus 112-115 15996188-5 2005 Furthermore, the percentages of the T cells isolated from the spleens of DBA/2 mice exposed to both mercury and LPS that produced pro-inflammatory cytokines were markedly increased by in vitro stimulation with phorbol myristate acetate (PMA) and ionomycin, which was not the case for splenic T cells isolated from mice receiving mercuric chloride, LPS or saline alone. Tetradecanoylphorbol Acetate 210-235 toll-like receptor 4 Mus musculus 348-351 15996188-5 2005 Furthermore, the percentages of the T cells isolated from the spleens of DBA/2 mice exposed to both mercury and LPS that produced pro-inflammatory cytokines were markedly increased by in vitro stimulation with phorbol myristate acetate (PMA) and ionomycin, which was not the case for splenic T cells isolated from mice receiving mercuric chloride, LPS or saline alone. Tetradecanoylphorbol Acetate 237-240 toll-like receptor 4 Mus musculus 112-115 15996188-5 2005 Furthermore, the percentages of the T cells isolated from the spleens of DBA/2 mice exposed to both mercury and LPS that produced pro-inflammatory cytokines were markedly increased by in vitro stimulation with phorbol myristate acetate (PMA) and ionomycin, which was not the case for splenic T cells isolated from mice receiving mercuric chloride, LPS or saline alone. Tetradecanoylphorbol Acetate 237-240 toll-like receptor 4 Mus musculus 348-351 15039304-5 2004 We found that TPA-differentiated U937 cells usually showed resistance to LPS-induced apoptosis. Tetradecanoylphorbol Acetate 14-17 toll-like receptor 4 Mus musculus 73-76 12584172-3 2003 We investigated the mutagenic potentials of 12-O-tetradecanoylphorbol-13-acetate (TPA)-stimulated differentiated HL-60 (human promyelocytic leukemia cells), and RAW 264.7 cells (murine macrophages) stimulated with lipopolysaccharide (LPS) and interferon (IFN)-gamma by co-culturing each cell line with AS52 cells, a transgenic Chinese hamster ovary cell line. Tetradecanoylphorbol Acetate 82-85 toll-like receptor 4 Mus musculus 234-237 12584172-5 2003 RAW 264.7 cells stimulated with LPS and IFN-gamma produced O(2)(-), nitric oxide (NO) and peroxynitrite (ONOO(-)) continuously for 5-25 h. There was a 2.0-fold increase in the mutation frequency of the gpt gene in AS52 cells co-cultured with TPA stimulated HL-60 cells, when compared with non-treated cells. Tetradecanoylphorbol Acetate 242-245 toll-like receptor 4 Mus musculus 32-35 10329111-2 1999 LPS pretreatment inhibits subsequent LPS-stimulated MAPK activation and TNF release and both were reversed if macrophages were treated with phorbol myristate acetate (PMA) before LPS stimulation. Tetradecanoylphorbol Acetate 140-165 toll-like receptor 4 Mus musculus 37-40 10329111-2 1999 LPS pretreatment inhibits subsequent LPS-stimulated MAPK activation and TNF release and both were reversed if macrophages were treated with phorbol myristate acetate (PMA) before LPS stimulation. Tetradecanoylphorbol Acetate 140-165 toll-like receptor 4 Mus musculus 37-40 10329111-2 1999 LPS pretreatment inhibits subsequent LPS-stimulated MAPK activation and TNF release and both were reversed if macrophages were treated with phorbol myristate acetate (PMA) before LPS stimulation. Tetradecanoylphorbol Acetate 167-170 toll-like receptor 4 Mus musculus 0-3 10329111-2 1999 LPS pretreatment inhibits subsequent LPS-stimulated MAPK activation and TNF release and both were reversed if macrophages were treated with phorbol myristate acetate (PMA) before LPS stimulation. Tetradecanoylphorbol Acetate 167-170 toll-like receptor 4 Mus musculus 37-40 10329111-2 1999 LPS pretreatment inhibits subsequent LPS-stimulated MAPK activation and TNF release and both were reversed if macrophages were treated with phorbol myristate acetate (PMA) before LPS stimulation. Tetradecanoylphorbol Acetate 167-170 toll-like receptor 4 Mus musculus 37-40 8604001-5 1996 This phenotype was stable and was specific to LPS since colony-stimulating factor 1 and phorbol myristate acetate had no effect on G418 resistance. Tetradecanoylphorbol Acetate 88-113 toll-like receptor 4 Mus musculus 46-49 8906745-4 1996 Our work demonstrates that: (1) resting B cells from mice containing the Yaa allele hyperproliferated compared to that seen with B cells from mice lacking the Yaa allele, (2) this hyperproliferation occurred whether cells were stimulated with phorbol myristate acetate/ionomycin, LPS, anti-IgM, or CD40L cross-linking, (3) this hyperproliferation is specific to B and not T cells. Tetradecanoylphorbol Acetate 243-268 toll-like receptor 4 Mus musculus 280-283 7790814-8 1995 Similarly, activation of DNA binding by the transcription factor, nuclear factor (NF) kappa B, as assessed by electrophoretic mobility shift assay, occurred in response to LPS stimulation but not in response to delta Raf-1:ER activation or phorbol myristate acetate (PMA) stimulation. Tetradecanoylphorbol Acetate 267-270 toll-like receptor 4 Mus musculus 172-175 1730783-13 1992 H-7 did inhibit induction of TPA responsive element binding by either LPS or PMA. Tetradecanoylphorbol Acetate 29-32 toll-like receptor 4 Mus musculus 70-73 7791343-10 1995 Pretreatment with PMA partially reproduced LPSp pretreatment. Tetradecanoylphorbol Acetate 18-21 toll-like receptor 4 Mus musculus 43-47 7921926-6 1994 One injection of macrophages cultured either in presence of LPS+TPA or of LPS+TPA+PGE2 resulted in marked slow-down of the tumor growth. Tetradecanoylphorbol Acetate 78-81 toll-like receptor 4 Mus musculus 74-77 1429672-5 1992 When 30 ng/ml 4-beta-phorbol-12-myristate 13-acetate (PMA) is added together with LPS, large amounts of TNF alpha are secreted. Tetradecanoylphorbol Acetate 14-52 toll-like receptor 4 Mus musculus 82-85 1379986-7 1992 LPS was found to inhibit thymocyte proliferation stimulated by concanavalin A or the combination of phorbol myristate acetate and ionomycin. Tetradecanoylphorbol Acetate 100-125 toll-like receptor 4 Mus musculus 0-3 3874870-9 1985 TPA, which also causes differentiation in these cells, and the synthetic diacylglycerol, 1-oleoyl-2-acetylglycerol, have opposite effects from LPS on both phosphatidylinositol turnover and cellular Ca+ mobilization. Tetradecanoylphorbol Acetate 0-3 toll-like receptor 4 Mus musculus 143-146 1709735-8 1991 Phorbol 12-myristate 13-acetate also stimulated protein tyrosine phosphorylation, but some of the modulated proteins were different than those phosphorylated by LPS. Tetradecanoylphorbol Acetate 0-31 toll-like receptor 4 Mus musculus 161-164 7350246-2 1980 Priming with LPS (1 microgram/ml) produced a sevenfold enhancement of PMA-stimulated O2- generation; priming was detected within 30 min and persisted for at least 4 d. Exposure to MDP (1 muM) primed the macrophages to double their O2- release; the response was first observed after 4 h and persisted for at least 3 d. The priming response was not observed with stereoisomers of MDP, which are inactive as adjuvants. Tetradecanoylphorbol Acetate 70-73 toll-like receptor 4 Mus musculus 13-16 6267131-2 1981 A 48-hr incubation of murine thioglycollate-elicited macrophages with LPS (0.1 micrograms/ml) resulted in an enhanced ability of these cells to produce oxygen radicals when challenged with phorbol myristate acetate (PMA). Tetradecanoylphorbol Acetate 189-214 toll-like receptor 4 Mus musculus 70-73 6267131-2 1981 A 48-hr incubation of murine thioglycollate-elicited macrophages with LPS (0.1 micrograms/ml) resulted in an enhanced ability of these cells to produce oxygen radicals when challenged with phorbol myristate acetate (PMA). Tetradecanoylphorbol Acetate 216-219 toll-like receptor 4 Mus musculus 70-73 30060484-3 2018 In this study, the anti-inflammatory effects of DA on the MAP kinase and NFkappaB signaling pathways and the expression of pro-inflammatory cytokines were investigated in phorbol 12-myristate 13-acetate (PMA)-activated human promyelocytic leukemia (HL-60) and lipopolysaccharide (LPS)-stimulated macrophage (Raw 264.7) cell lines. Tetradecanoylphorbol Acetate 204-207 toll-like receptor 4 Mus musculus 280-283 27057457-6 2016 Using a highly metastatic Hgf-Cdk4(R24C) melanoma skin transplant we could show that TPA enhances systemic spread of melanoma cells which was depended on intact TLR4 signaling in recipient mice and on the presence of neutrophils. Tetradecanoylphorbol Acetate 85-88 toll-like receptor 4 Mus musculus 161-165