PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17027084-2 2007 Here, we found that phorbol 12-myristate 13-acetate (PMA) alone did not induce IL-3 gene expression, but potentiated A23187-induced IL-3 gene expression. Tetradecanoylphorbol Acetate 20-51 interleukin 3 Mus musculus 132-136 17027084-2 2007 Here, we found that phorbol 12-myristate 13-acetate (PMA) alone did not induce IL-3 gene expression, but potentiated A23187-induced IL-3 gene expression. Tetradecanoylphorbol Acetate 53-56 interleukin 3 Mus musculus 132-136 8258682-8 1993 They displayed potent cytolytic activity against NK-sensitive targets, and, when stimulated with PMA+ionomycin, secreted IL-3 and IFN-gamma, but not IL-2 or IL-4. Tetradecanoylphorbol Acetate 97-100 interleukin 3 Mus musculus 121-125 15355467-8 2004 Nonspecific stimulus with calcium ionophore and phorbol-myristate-acetate of BM CD34(+) cells caused release of IL-5, IL-3 and GM-CSF. Tetradecanoylphorbol Acetate 48-73 interleukin 3 Mus musculus 118-122 15252114-6 2004 In the presence of IL-3, PMA dramatically reduced the phosphorylation of residues 31 and 118, which was accompanied by inhibition of cell polarization and motility. Tetradecanoylphorbol Acetate 25-28 interleukin 3 Mus musculus 19-23 10199555-6 1999 Similar to the IL-3 withdrawal, phorbol 12-myristate 13-acetate (PMA) dissolves actin-formed membrane ruffles and rounds the cells in the presence of IL-3. Tetradecanoylphorbol Acetate 32-63 interleukin 3 Mus musculus 150-154 10199555-6 1999 Similar to the IL-3 withdrawal, phorbol 12-myristate 13-acetate (PMA) dissolves actin-formed membrane ruffles and rounds the cells in the presence of IL-3. Tetradecanoylphorbol Acetate 65-68 interleukin 3 Mus musculus 15-19 10199555-6 1999 Similar to the IL-3 withdrawal, phorbol 12-myristate 13-acetate (PMA) dissolves actin-formed membrane ruffles and rounds the cells in the presence of IL-3. Tetradecanoylphorbol Acetate 65-68 interleukin 3 Mus musculus 150-154 8996200-3 1997 Although TPA alone did not support colony formation, TPA in combination with IL-3 increased colony numbers from 1.5 to 2 times that formed with IL-3 and vehicle. Tetradecanoylphorbol Acetate 53-56 interleukin 3 Mus musculus 144-148 8996200-6 1997 Because TPA enhanced IL-3-dependent colony formation derived from lineage-negative marrow cells obtained from mice that received 5-FU 2 days before, it is possible that it might act directly on primitive progenitors. Tetradecanoylphorbol Acetate 8-11 interleukin 3 Mus musculus 21-25 8996200-8 1997 Calphostin C, a specific PKC inhibitor, and certain specific tyrosine kinase inhibitors, such as genistein and herbimycin A, abrogated the enhancing effects of TPA on IL-3-dependent colony formation. Tetradecanoylphorbol Acetate 160-163 interleukin 3 Mus musculus 167-171 8996200-9 1997 These data suggest that TPA had a direct effect on the primitive progenitors and enhanced IL-3-dependent colony formation via activation of PKC and certain tyrosine kinases. Tetradecanoylphorbol Acetate 24-27 interleukin 3 Mus musculus 90-94 7868057-3 1994 When colony numbers were compared with those supported by IL-3, IL-6+TPA gave rise to 86 + 47% of colonies formed with IL-3. Tetradecanoylphorbol Acetate 69-72 interleukin 3 Mus musculus 58-62 7868057-3 1994 When colony numbers were compared with those supported by IL-3, IL-6+TPA gave rise to 86 + 47% of colonies formed with IL-3. Tetradecanoylphorbol Acetate 69-72 interleukin 3 Mus musculus 119-123 10688817-5 2000 The target for this inhibition was Jak2, and the activation of PKC by 12-O-tetradecanoyl-phorbol-13-acetate treatment also abrogated IL-3-induced tyrosine phosphorylation of Jak2 in Ba/F3 cells. Tetradecanoylphorbol Acetate 70-107 interleukin 3 Mus musculus 133-137 8208545-1 1994 FD/PMA, a derivative of the interleukin-3 (IL-3) dependent FDC-P1 cell line, proliferates in response to either phorbol esters (phorbol 12-myristate 13-acetate, PMA) or IL-3. Tetradecanoylphorbol Acetate 3-6 interleukin 3 Mus musculus 28-41 8208545-1 1994 FD/PMA, a derivative of the interleukin-3 (IL-3) dependent FDC-P1 cell line, proliferates in response to either phorbol esters (phorbol 12-myristate 13-acetate, PMA) or IL-3. Tetradecanoylphorbol Acetate 3-6 interleukin 3 Mus musculus 43-47 8208545-1 1994 FD/PMA, a derivative of the interleukin-3 (IL-3) dependent FDC-P1 cell line, proliferates in response to either phorbol esters (phorbol 12-myristate 13-acetate, PMA) or IL-3. Tetradecanoylphorbol Acetate 3-6 interleukin 3 Mus musculus 169-173 2575077-1 1989 A mixture of phorbol myristate acetate (PMA) and ionomycin was found to stimulate spleen and lymph node cells (LNC) from 6 to 8 week-old-athymic BALB/c nude mice, as well as from control +/+ mice, to secrete interleukin-3 (IL-3) in vitro. Tetradecanoylphorbol Acetate 13-38 interleukin 3 Mus musculus 208-221 1824257-1 1991 FD/PMA is a subclone of the interleukin-3 (IL-3)-dependent, FDC-P1 cell line, which proliferates in response to either 12-O-tetradecanoylphorbol-13 acetate (PMA) or IL-3. Tetradecanoylphorbol Acetate 119-155 interleukin 3 Mus musculus 28-41 1824257-1 1991 FD/PMA is a subclone of the interleukin-3 (IL-3)-dependent, FDC-P1 cell line, which proliferates in response to either 12-O-tetradecanoylphorbol-13 acetate (PMA) or IL-3. Tetradecanoylphorbol Acetate 119-155 interleukin 3 Mus musculus 43-47 1824257-1 1991 FD/PMA is a subclone of the interleukin-3 (IL-3)-dependent, FDC-P1 cell line, which proliferates in response to either 12-O-tetradecanoylphorbol-13 acetate (PMA) or IL-3. Tetradecanoylphorbol Acetate 3-6 interleukin 3 Mus musculus 28-41 1824257-1 1991 FD/PMA is a subclone of the interleukin-3 (IL-3)-dependent, FDC-P1 cell line, which proliferates in response to either 12-O-tetradecanoylphorbol-13 acetate (PMA) or IL-3. Tetradecanoylphorbol Acetate 3-6 interleukin 3 Mus musculus 43-47 1824257-1 1991 FD/PMA is a subclone of the interleukin-3 (IL-3)-dependent, FDC-P1 cell line, which proliferates in response to either 12-O-tetradecanoylphorbol-13 acetate (PMA) or IL-3. Tetradecanoylphorbol Acetate 3-6 interleukin 3 Mus musculus 165-169 2266115-6 1990 Activation of PKC by phorbol myristate acetate causes inhibition of IL-3-mediated growth for the first 72 h of incubation. Tetradecanoylphorbol Acetate 21-46 interleukin 3 Mus musculus 68-72 2266115-7 1990 The inhibition in IL-3-mediated proliferation gradually lessens with the stages of PKC depletion, which is complete after 72 h. The enhancement in phorbol myristate acetate-treated cells grows as PKC is depleted. Tetradecanoylphorbol Acetate 147-172 interleukin 3 Mus musculus 18-22 2575077-1 1989 A mixture of phorbol myristate acetate (PMA) and ionomycin was found to stimulate spleen and lymph node cells (LNC) from 6 to 8 week-old-athymic BALB/c nude mice, as well as from control +/+ mice, to secrete interleukin-3 (IL-3) in vitro. Tetradecanoylphorbol Acetate 40-43 interleukin 3 Mus musculus 223-227 2575077-1 1989 A mixture of phorbol myristate acetate (PMA) and ionomycin was found to stimulate spleen and lymph node cells (LNC) from 6 to 8 week-old-athymic BALB/c nude mice, as well as from control +/+ mice, to secrete interleukin-3 (IL-3) in vitro. Tetradecanoylphorbol Acetate 13-38 interleukin 3 Mus musculus 223-227 2575077-1 1989 A mixture of phorbol myristate acetate (PMA) and ionomycin was found to stimulate spleen and lymph node cells (LNC) from 6 to 8 week-old-athymic BALB/c nude mice, as well as from control +/+ mice, to secrete interleukin-3 (IL-3) in vitro. Tetradecanoylphorbol Acetate 40-43 interleukin 3 Mus musculus 208-221 2644975-0 1989 Interleukin-3, GM-CSF, and TPA induce distinct phosphorylation events in an interleukin 3-dependent multipotential cell line. Tetradecanoylphorbol Acetate 27-30 interleukin 3 Mus musculus 76-89 2565932-3 1989 Although the latter cells strongly proliferate in response to phorbol myristate acetate (PMA) + ionomycin, DETC, when exposed to interleukin-1 (IL-1), interleukin-3 (IL-3), concanavalin A (ConA), PMA, and ionomycin used either alone or in combination, do not exhibit significant mitotic activity. Tetradecanoylphorbol Acetate 89-92 interleukin 3 Mus musculus 151-164 2644975-3 1989 In addition, sodium orthovanadate, an inhibitor of phosphotyrosine phosphatase, and 12-O-tetradecanoyl-phorbol-13-acetate (TPA), a known activator of protein kinase C, also stimulated DNA synthesis in these cells, suggesting that protein phosphorylation might be involved in the mechanism of action of mIL-3 and mGM-CSF. Tetradecanoylphorbol Acetate 84-121 interleukin 3 Mus musculus 302-307 2453228-6 1988 CSF-1, GM-CSF, and IL-3 could also synergize with TPA; CSF-1 cooperated with 1-oleoyl-2-acetylglycerol (OAG), both sets of results pointing to an interaction with protein kinase C. LPS completely abolished the CSF-1-mediated stimulation of DNA synthesis. Tetradecanoylphorbol Acetate 50-53 interleukin 3 Mus musculus 19-23 3142956-6 1988 The tumor-promoting phorbol diester, 12-o-tetradecanoyl-phorbol-13-acetate (TPA) also acted synergistically with the three CSFs (IL-3, GM-CSF, and M-CSF) to stimulate the proliferation of BDM-1 cells. Tetradecanoylphorbol Acetate 37-74 interleukin 3 Mus musculus 129-133 3142956-6 1988 The tumor-promoting phorbol diester, 12-o-tetradecanoyl-phorbol-13-acetate (TPA) also acted synergistically with the three CSFs (IL-3, GM-CSF, and M-CSF) to stimulate the proliferation of BDM-1 cells. Tetradecanoylphorbol Acetate 76-79 interleukin 3 Mus musculus 129-133 3142956-7 1988 The synergistic effect was observed when cells were pretreated with TPA and subsequently stimulated with IL-3. Tetradecanoylphorbol Acetate 68-71 interleukin 3 Mus musculus 105-109 3158821-4 1985 Phorbol myristate acetate (PMA) is shown to have a similar effect in these IL-3-dependent FDC-P1 cells. Tetradecanoylphorbol Acetate 0-25 interleukin 3 Mus musculus 75-79 3129045-9 1988 Phorbol myristate acetate (PMA) stimulated FDC-P1 cells and was able to abrogate the PT inhibition of IL 3 stimulation of these cells, suggesting but not establishing that IL 3 may mediate its proliferative effects through activating protein kinase C. Tetradecanoylphorbol Acetate 0-25 interleukin 3 Mus musculus 102-106 3129045-9 1988 Phorbol myristate acetate (PMA) stimulated FDC-P1 cells and was able to abrogate the PT inhibition of IL 3 stimulation of these cells, suggesting but not establishing that IL 3 may mediate its proliferative effects through activating protein kinase C. Tetradecanoylphorbol Acetate 27-30 interleukin 3 Mus musculus 102-106 3129045-9 1988 Phorbol myristate acetate (PMA) stimulated FDC-P1 cells and was able to abrogate the PT inhibition of IL 3 stimulation of these cells, suggesting but not establishing that IL 3 may mediate its proliferative effects through activating protein kinase C. Tetradecanoylphorbol Acetate 27-30 interleukin 3 Mus musculus 172-176 3158821-4 1985 Phorbol myristate acetate (PMA) is shown to have a similar effect in these IL-3-dependent FDC-P1 cells. Tetradecanoylphorbol Acetate 27-30 interleukin 3 Mus musculus 75-79 3917479-8 1985 EC IL 3 production was greatly enhanced by the addition of concanavalin A, phorbol myristate acetate, lipopolysaccharide, and silica. Tetradecanoylphorbol Acetate 75-100 interleukin 3 Mus musculus 3-7