PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20561592-7 2010 A reduction on brain-derived neurotrophic factor immunocontent and increased acetylcholinesterase activity in prefrontal cortex, but not in hippocampus, of rats treated with methylphenidate were also observed. Methylphenidate 174-189 acetylcholinesterase Rattus norvegicus 77-97 35598825-0 2022 Effects of methylphenidate after a long period of discontinuation include changes in exploratory behavior and increases brain activities of Na+,K+-ATPase and acetylcholinesterase. Methylphenidate 11-26 acetylcholinesterase Rattus norvegicus 158-178 20561592-8 2010 These results suggest that the deficit in spatial memory may be associated to decreased brain-derived neurotrophic factor immunocontent and increased acetylcholinesterase in prefrontal cortex of juvenile rats subjected to methylphenidate administration. Methylphenidate 222-237 acetylcholinesterase Rattus norvegicus 150-170