PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15838284-5	2004	In CHO-SerET(A)R or CHO-ET(A)R pretreated with U73122, an inhibitor of phospholipase C, ET-1 activated NSCC-1.	CAV protocol	3-6	endothelin-1	Cricetulus griseus	88-92	
22504006-2	2012	We determined that ET-1 activation of its ETB receptor in stably cDNA transfected CHO cells leads to a 55% reduction in cell number by end-point cell counting and a 35% decrease in cell growth by a real-time cell-substrate impedance-based assay after 24h of cell growth.	CAV protocol	82-85	endothelin-1	Cricetulus griseus	19-23	
22504006-3	2012	When CHO ETB cells were synchronized in the late G1 cell cycle phase, ET-1 delayed their S phase progression compared to control by 30% as determined by [(3)H]-thymidine incorporation.	CAV protocol	5-8	endothelin-1	Cricetulus griseus	70-74	
12920205-9	2003	ET-1 also induced AA release in CHO cells expressing ETAR truncated at the carboxyl terminal downstream of Cys385 (CHO-ETARDelta385) or an unpalmitoylated (Cys383 Cys385-388--> Ser383Ser385-388) ETAR (CHO-SerETAR), each of which is coupled with Gq or Gs/G12, respectively.	CAV protocol	32-35	endothelin-1	Cricetulus griseus	0-4	
12920205-12	2003	These results indicate the following: 1) ET-1-induced AA release depends on Ca2+ influx through NSCC-1, NSCC-2, and SOCC in CHO-ETAR; 2) Gq and G12 mediate AA release through ETAR in CHO cells; and 3) PI3K is involved in ET-1-induced AA release, which depends on NSCC-2 and SOCC.	CAV protocol	124-127	endothelin-1	Cricetulus griseus	41-45	
1662495-6	1991	Et-1 displaced Et-1[BtK9] binding to VSMC and CHO[EtR] to a greater extent than endothelin-3, indicating predominant expression of EtA receptor sub-type.	CAV protocol	46-49	endothelin-1	Cricetulus griseus	0-4	
7487910-9	1995	Intact COS or CHO cells transfected with ECE cDNA rapidly and efficiently cleaved big endothelin-1 added to the culture medium.	CAV protocol	14-17	endothelin-1	Cricetulus griseus	86-98