PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19526291-0 2009 Glyceraldehyde-3-phosphate dehydrogenase-monoamine oxidase B-mediated cell death-induced by ethanol is prevented by rasagiline and 1-R-aminoindan. 1-r-aminoindan 131-145 monoamine oxidase B Homo sapiens 41-60 19526291-6 2009 In contrast, the MAO B inhibitors rasagiline and selegiline (0.25 nM) and the rasagiline metabolite, 1-R-aminoindan (1 muM) decreases the ethanol-induced MAO B, prevents nuclear translocation of GAPDH and reduces cell death. 1-r-aminoindan 101-115 monoamine oxidase B Homo sapiens 154-159 19526291-7 2009 In addition, GAPDH interacts with transforming growth factor-beta-inducible early gene (TIEG2), a transcriptional activator for MAO B, and this interaction is increased in the nucleus by ethanol but reduced by MAO B inhibitors and 1-R-aminoindan. 1-r-aminoindan 231-245 monoamine oxidase B Homo sapiens 128-133 19526291-10 2009 Thus, the neuroprotective effects of rasagiline or 1-R-aminoindan on ethanol-induced cell death mediated by a novel GAPDH-MAO B pathway may provide a new insight in the treatment of neurobiological diseases including alcohol-use disorders. 1-r-aminoindan 51-65 monoamine oxidase B Homo sapiens 122-127