PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30586693-0	2019	Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.	Indican	13-28	delta like canonical Notch ligand 4	Mus musculus	109-113	
30586693-12	2019	As predicted computationally, indoxyl sulfate triggered Notch signaling, which was preceded by the rapid induction of Dll4 protein.	Indican	30-45	delta like canonical Notch ligand 4	Mus musculus	118-122	
30586693-14	2019	In mice, macrophage-targeted OATP2B1/Slco2b1 silencing and Dll4 antibody inhibited proinflammatory activation of peritoneal macrophages induced by indoxyl sulfate.	Indican	147-162	delta like canonical Notch ligand 4	Mus musculus	59-63	
30586693-17	2019	CONCLUSIONS: These results suggest that novel crosstalk between OATP2B1 and Dll4-Notch signaling in macrophages mediates indoxyl sulfate-induced vascular inflammation in CKD.	Indican	121-136	delta like canonical Notch ligand 4	Mus musculus	76-80