PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24440401-3	2014	[14C]-erythromycin was selected as a model substrate to study interaction of quinidine and Ile-quinidine with P-gp.	Erythromycin	6-18	PGP	Canis lupus familiaris	110-114	
24440401-6	2014	This result indicates that [14C]-erythromycin is an excellent substrate of P-gp.	Erythromycin	33-45	PGP	Canis lupus familiaris	75-79	
20573570-6	2010	[(14)C] Erythromycin was selected as a model substrate for P-gp and MRP2 whereas Hoechst 33342 was employed as a substrate for BCRP.	Erythromycin	8-20	PGP	Canis lupus familiaris	59-63	
18958406-5	2009	RESULTS: Bi-directional transport of erythromycin across MDCK-MDR1 and MDCK-MRP2 cells showed significant difference between BL-AP and AP-BL permeability, suggesting that erythromycin is a substrate for P-gp and MRP2.	Erythromycin	37-49	PGP	Canis lupus familiaris	203-207	
18958406-5	2009	RESULTS: Bi-directional transport of erythromycin across MDCK-MDR1 and MDCK-MRP2 cells showed significant difference between BL-AP and AP-BL permeability, suggesting that erythromycin is a substrate for P-gp and MRP2.	Erythromycin	171-183	PGP	Canis lupus familiaris	203-207	
18958406-8	2009	Even, steroids inhibited P-gp and MRP2 mediated efflux with maximum increase in k(a), AUC(0-infinity), C(max) and C(last) values of erythromycin, observed with 6alpha-methyl prednisolone.	Erythromycin	132-144	PGP	Canis lupus familiaris	25-29	
18958406-10	2009	Steroids were able to significantly inhibit both P-gp and MRP2 mediated efflux of erythromycin.	Erythromycin	82-94	PGP	Canis lupus familiaris	49-53	
16455803-2	2006	To investigate possible interaction mechanisms, the effects of erythromycin on active transport mediated by P-glycoprotein (P-gp) in vitro in Caco-2 and P-gp-over-expressing Madin-Darby canine kidney-human multidrug resistance-1 cell preparations and on biliary excretion of melagatran in rats were studied.	Erythromycin	63-75	PGP	Canis lupus familiaris	108-122	
16455803-2	2006	To investigate possible interaction mechanisms, the effects of erythromycin on active transport mediated by P-glycoprotein (P-gp) in vitro in Caco-2 and P-gp-over-expressing Madin-Darby canine kidney-human multidrug resistance-1 cell preparations and on biliary excretion of melagatran in rats were studied.	Erythromycin	63-75	PGP	Canis lupus familiaris	124-128	
15175422-8	2004	Erythromycin exhibited significant efflux out of MDCK-MDR1 cells, suggesting that erythromycin is a good substrate for P-gp.	Erythromycin	0-12	PGP	Canis lupus familiaris	119-123	
15175422-8	2004	Erythromycin exhibited significant efflux out of MDCK-MDR1 cells, suggesting that erythromycin is a good substrate for P-gp.	Erythromycin	82-94	PGP	Canis lupus familiaris	119-123