PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12829454-5 2003 CAM and erythromycin significantly inhibited spontaneous and tumor necrosis factor-alpha (20 ng/ml)-induced mucus secretion from NCI-H292 cells at 10-6 to 10-7 M and from human nasal epithelial cells at 10-4 to 10-5 M. MUC5AC messenger RNA expression was also significantly inhibited. Erythromycin 8-20 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 219-225 18339018-0 2008 Erythromycin attenuates MUC5AC synthesis and secretion in cultured human tracheal cells infected with RV14. Erythromycin 0-12 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 24-30 18339018-6 2008 RESULTS: Erythromycin blocked RV14-induced MUC5AC protein overproduction and hypersecretion, and also blocked RV14-induced p44/42 MAPK activation in the cells. Erythromycin 9-21 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 43-49 18339018-7 2008 CONCLUSIONS: Erythromycin may attenuate RV14-induced MUC5AC overproduction and hypersecretion by blocking the p44/42 MAPK pathway or its upstream regulators. Erythromycin 13-25 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 53-59 25769240-9 2015 EM900, CAM, or erythromycin significantly inhibited MUC5AC secretion induced by tumor necrosis factor-alpha from NCI-H292 cells. Erythromycin 15-27 mucin 5AC, oligomeric mucus/gel-forming Homo sapiens 52-58