PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8575568-0	1995	Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells.	Erythromycin	10-22	interleukin 6	Homo sapiens	78-82	
28584401-4	2017	We first confirmed that erythromycin suppresses the transcriptional activity of nuclear factor-kappaB and activator protein-1 and the expression of its downstream targets, interleukin-6 and cyclooxygenase-2 in human colon cancer cells.	Erythromycin	24-36	interleukin 6	Homo sapiens	172-185	
8575568-5	1995	Incubation of the epithelial cultures in the presence of 0.1-10 micrograms.mL-1 erythromycin significantly blocked the HIE-induced release of IL-6, IL-8, and sICAM-1, at all concentrations of erythromycin investigated.	Erythromycin	80-92	interleukin 6	Homo sapiens	142-146	
1759822-0	1991	Differential modulation of cytokine production by macrolides: interleukin-6 production is increased by spiramycin and erythromycin.	Erythromycin	118-130	interleukin 6	Homo sapiens	62-75	
7763252-0	1995	Erythromycin suppresses interleukin 6 expression by human bronchial epithelial cells: a potential mechanism of its anti-inflammatory action.	Erythromycin	0-12	interleukin 6	Homo sapiens	24-37	
7763252-2	1995	Among those tested, erythromycin (EM) and clarithromycin (CAM) uniquely suppressed mRNA levels as well as the release of IL-6 at the therapeutic and non-cytotoxic concentration (10(-6)M).	Erythromycin	20-32	interleukin 6	Homo sapiens	121-125	
7763252-2	1995	Among those tested, erythromycin (EM) and clarithromycin (CAM) uniquely suppressed mRNA levels as well as the release of IL-6 at the therapeutic and non-cytotoxic concentration (10(-6)M).	Erythromycin	34-36	interleukin 6	Homo sapiens	121-125	
8309727-7	1993	Among the same family of antibiotics such as macrolides, differences on cytokine modulation were observed: spiramycin and erythromycin increased IL-6 production while roxithromycin did not exert any significant effect.	Erythromycin	122-134	interleukin 6	Homo sapiens	145-149	
1759822-5	1991	Spiramycin and, to a lesser extent, erythromycin increased total IL-6 production without affecting IL-1 alpha, IL-1 beta, or tumor necrosis factor alpha production, whereas roxithromycin had no effect.	Erythromycin	36-48	interleukin 6	Homo sapiens	65-69	
1759822-3	1991	We compared the in vitro effects of three macrolides (roxithromycin, spiramycin, and erythromycin) actively concentrated by leukocytes on interleukin-1 alpha, (IL-1 alpha), IL-1 beta, IL-6, and tumor necrosis factor alpha production by human monocytes stimulated with lipopolysaccharide.	Erythromycin	85-97	interleukin 6	Homo sapiens	184-188