PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20877800-4 2009 Clearly, the rapid formation of adenine by aqueous polymerization of HCN is one of the key discoveries in these experiments. Adenine 32-39 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 69-72 17630841-0 2007 Adenine synthesis in interstellar space: mechanisms of prebiotic pyrimidine-ring formation of monocyclic HCN-pentamers. Adenine 0-7 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 105-108 17951429-2 2007 Thus, the HCN pentamer, adenine (a base present in DNA and RNA), was first isolated in abiogenic experiments from an aqueous solution of ammonia and HCN in 1960. Adenine 24-31 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 10-13 17951429-2 2007 Thus, the HCN pentamer, adenine (a base present in DNA and RNA), was first isolated in abiogenic experiments from an aqueous solution of ammonia and HCN in 1960. Adenine 24-31 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 149-152 17630841-2 2007 Adenine is formally the HCN pentamer, and experiments have demonstrated that adenine is formed under certain conditions by HCN pentamerization in gas, liquid, and condensed phases. Adenine 0-7 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 24-27 17630841-2 2007 Adenine is formally the HCN pentamer, and experiments have demonstrated that adenine is formed under certain conditions by HCN pentamerization in gas, liquid, and condensed phases. Adenine 77-84 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 24-27 17630841-2 2007 Adenine is formally the HCN pentamer, and experiments have demonstrated that adenine is formed under certain conditions by HCN pentamerization in gas, liquid, and condensed phases. Adenine 77-84 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 123-126 17630841-3 2007 Most mechanistic proposals invoke the intermediacy of the HCN tetramer AICN (4), and it is thought that adenine synthesis is completed by addition of the 5(th) HCN to 4 to form amidine 5 and subsequent pyrimidine cyclization. Adenine 104-111 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 160-163 6462692-3 1984 Prebiotic syntheses of adenine from HCN, of D,L-ribose from adenosine, and of adenosine from adenine and D-ribose have in fact been demonstrated. Adenine 23-30 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 36-39 15103102-13 2004 The dissociation reactions of deprotonated adenine, however, proceed by elimination of HCN and (2) elimination of NCHNH (NCHND). Adenine 43-50 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 87-90 11536683-6 1995 These properties include the following: (1) Adenine synthesis requires HCN concentrations of at least 0.01 M. Such concentrations would be expected only in unique circumstances on the early Earth. Adenine 45-52 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 72-75 33579010-5 2021 An example is given of photochemical dissipative abiogenesis of adenine from the precursor HCN in water solvent within a fatty acid vesicle floating on a hot ocean surface and driven far from equilibrium by the incident UVC light. Adenine 64-71 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 91-94 6291673-0 1982 Prebiotic adenine synthesis via HCN oligomerization in ice. Adenine 10-17 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 32-35 6291673-1 1982 Adenine is produced (after hydrolysis) when 0.01 M solutions of HCN are adjusted to pH 9.2 with NH4OH and are frozen at -2 degrees C for 60-100 days. Adenine 0-7 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 64-67 32289197-10 2020 In photochemical conditions, the conjunction of the imines and its dissociation products (HCN and CNH) yields adenine. Adenine 110-117 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 90-93 24796654-1 2014 From a historic point of view adenine was always presumed to be the product of HCN pentamerization. Adenine 30-37 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 79-82 27518115-3 2017 Since the first prebiotic synthesis of adenine by Oro, HCN polymers have gained much interest in studies on the origins of life due to the identification of biomonomers and related compounds within them. Adenine 39-46 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 55-58 25559322-7 2015 Deprotonated adenine fragments by loss of hydrogen cyanide and/or isocyanide (HCN/HNC; 90%) and carbodiimide (HNCNH) and/or cyanamide (NH2CN; 10%). Adenine 13-20 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 78-81 25559322-8 2015 Tandem mass spectrometry (MS(n)) experiments reveal that deprotonated guanine fragments lose additional HCN and CO, while deprotonated adenine fragments successively lose HNC and HCN. Adenine 135-142 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 179-182 24796654-2 2014 In this work a new mechanism for adenine synthesis in the gas phase without HCN is proposed. Adenine 33-40 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 76-79