PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8240067-5 1993 There was an 18% decrease of beta 2M clearance in the period from 30 to 180 min with a time-averaged beta 2M clearance of 48 ml/min using polysulfone dialyzers (F80). polysulfone P 1700 138-149 beta-2-microglobulin Homo sapiens 29-36 8177478-4 1994 Associated with beta 2-microglobulin removal was a protein loss which averaged 2636 mg for Diaphan, 4937 mg for CTA, and 2500 mg for polysulphone. polysulfone P 1700 133-145 beta-2-microglobulin Homo sapiens 16-36 8144998-8 1994 At very low levels of intrinsic GFR (< 2.1 ml/min), hemodialysis patients using polysulfone dialyzers had lower levels of serum beta 2M than hemodialysis patients using cellulose-based dialyzers; CAPD patients also had lower levels of serum beta 2M than cellulose dialyzer-treated hemodialysis patients when the intrinsic GFR was less than 2.1 ml/min. polysulfone P 1700 83-94 beta-2-microglobulin Homo sapiens 131-138 8144998-8 1994 At very low levels of intrinsic GFR (< 2.1 ml/min), hemodialysis patients using polysulfone dialyzers had lower levels of serum beta 2M than hemodialysis patients using cellulose-based dialyzers; CAPD patients also had lower levels of serum beta 2M than cellulose dialyzer-treated hemodialysis patients when the intrinsic GFR was less than 2.1 ml/min. polysulfone P 1700 83-94 beta-2-microglobulin Homo sapiens 244-251 8144998-13 1994 At extremely low levels of GFR, use of polysulfone dialyzers or CAPD may lead to lower levels of serum beta 2M. polysulfone P 1700 39-50 beta-2-microglobulin Homo sapiens 103-110 8240067-5 1993 There was an 18% decrease of beta 2M clearance in the period from 30 to 180 min with a time-averaged beta 2M clearance of 48 ml/min using polysulfone dialyzers (F80). polysulfone P 1700 138-149 beta-2-microglobulin Homo sapiens 101-108 8465821-0 1993 The effect of dialyzer reprocessing on performance and beta 2-microglobulin removal using polysulfone membranes. polysulfone P 1700 90-101 beta-2-microglobulin Homo sapiens 55-75 8465821-2 1993 The impact of longer-term reprocessing is critical to the practical use of polysulfone membranes (PMs), because of the possibility of decreasing efficiency and performance, especially in the removal of beta 2-microglobulin (beta 2M), a protein that has been implicated in the development of dialysis-associated amyloidosis (DDA). polysulfone P 1700 75-86 beta-2-microglobulin Homo sapiens 202-222 8465821-2 1993 The impact of longer-term reprocessing is critical to the practical use of polysulfone membranes (PMs), because of the possibility of decreasing efficiency and performance, especially in the removal of beta 2-microglobulin (beta 2M), a protein that has been implicated in the development of dialysis-associated amyloidosis (DDA). polysulfone P 1700 75-86 beta-2-microglobulin Homo sapiens 224-231 1457695-3 1992 In contrast to the cuprophane membrane, the polysulfone membrane eliminated considerable amounts of beta 2-M. polysulfone P 1700 44-55 beta-2-microglobulin Homo sapiens 100-108 1585930-0 1992 The effects of reprocessing high-flux polysulfone dialyzers with peroxyacetic acid on beta 2-microglobulin removal in hemodiafiltration. polysulfone P 1700 38-49 beta-2-microglobulin Homo sapiens 86-106 1585930-8 1992 We then assessed prospectively the performance of 26 polysulfone dialyzers after peroxyacetic acid reprocessing up to 20 times, particularly with regard to their ability to remove beta 2M. polysulfone P 1700 53-64 beta-2-microglobulin Homo sapiens 180-187 2702129-0 1989 Fate of beta-2-microglobulin during dialysis on polysulfone and AN69 membranes. polysulfone P 1700 48-59 beta-2-microglobulin Homo sapiens 8-28 2655439-4 1989 Mean serum beta 2M (corrected for ultrafiltration) decreased by 16.6% +/- 18.1% with new cuprammonium dialyzers and 57.1% +/- 12.8% with new polysulfone dialyzers. polysulfone P 1700 141-152 beta-2-microglobulin Homo sapiens 11-18 2655439-6 1989 Predialysis serum beta 2M decreased by 30.4% +/- 15.5% 1 month after switching from cuprammonium to polysulfone dialyzers; these levels remained stable after 3 months of dialysis with polysulfone. polysulfone P 1700 100-111 beta-2-microglobulin Homo sapiens 18-25 2655439-6 1989 Predialysis serum beta 2M decreased by 30.4% +/- 15.5% 1 month after switching from cuprammonium to polysulfone dialyzers; these levels remained stable after 3 months of dialysis with polysulfone. polysulfone P 1700 184-195 beta-2-microglobulin Homo sapiens 18-25 2655439-8 1989 In vitro adsorption of 124I-beta 2M to polysulfone fibers was greater than to cuprammonium; adsorption was not influenced by dialyzer reprocessing. polysulfone P 1700 39-50 beta-2-microglobulin Homo sapiens 28-35 2646507-7 1989 In acute studies, beta 2M clearance during hemodialysis was markedly increased using the Fresenius polysulfone dialyzers compared to cuprophane dialyzers. polysulfone P 1700 99-110 beta-2-microglobulin Homo sapiens 18-25 2643313-5 1989 In patients receiving conventional hemodialysis using cellulose acetate membrane, beta 2M levels increased 25.4% after hemodialysis, whereas in patients receiving HF hemodialysis using polysulfone membrane, beta 2M levels decreased significantly (43.0%) after hemodialysis. polysulfone P 1700 185-196 beta-2-microglobulin Homo sapiens 207-214 1992659-0 1991 The effects of reprocessing cuprophane and polysulfone dialyzers on beta 2-microglobulin removal from hemodialysis patients. polysulfone P 1700 43-54 beta-2-microglobulin Homo sapiens 68-88 1992659-8 1991 Dialysis with high-flux polysulfone new dialyzers during the primary-use phase was associated with a decrease of 59.5% in the mean postdialysis concentration of serum beta 2M compared with the predialysis level. polysulfone P 1700 24-35 beta-2-microglobulin Homo sapiens 167-174 1992659-9 1991 A corresponding decrease of 62.6% in serum beta 2M levels was observed after dialysis with high-flux polysulfone reprocessed dialyzers during the reuse phase. polysulfone P 1700 101-112 beta-2-microglobulin Homo sapiens 43-50 1992659-11 1991 The results confirm previous studies that have reported that high-flux dialysis with polysulfone dialyzers removes substantial amounts of beta 2M, and dialysis with conventional cuprophane dialyzers does not. polysulfone P 1700 85-96 beta-2-microglobulin Homo sapiens 138-145 2264202-1 1990 The authors studied changes of the beta 2-microglobulin level during hemodialysis with dialyzers AIP-02-02 (cuprophane membrane), E2 (cuprophane membrane), AIP-03-02 (polysulfone membrane), F60 (polysulfone membrane), and hemodiafiltration with dialyzer F60. polysulfone P 1700 167-178 beta-2-microglobulin Homo sapiens 35-55 2264202-1 1990 The authors studied changes of the beta 2-microglobulin level during hemodialysis with dialyzers AIP-02-02 (cuprophane membrane), E2 (cuprophane membrane), AIP-03-02 (polysulfone membrane), F60 (polysulfone membrane), and hemodiafiltration with dialyzer F60. polysulfone P 1700 195-206 beta-2-microglobulin Homo sapiens 35-55 2197235-0 1990 Beta 2-microglobulin elimination characteristics during hemofiltration with acrylonitrile and polysulfone membrane hemofilters. polysulfone P 1700 94-105 beta-2-microglobulin Homo sapiens 0-20 2198889-8 1990 There was a sharp drop in the serum levels of beta 2-microglobulin during dialysis with both membranes (Polyflux 130: -46%; Polysulfone 600: -48%). polysulfone P 1700 124-135 beta-2-microglobulin Homo sapiens 46-66 2198889-10 1990 Both membranes were capable to remove large quantities of beta 2-microglobulin, amounting to 235 +/- 11 and 250 +/- 10 mg/4 h of dialysis for Polyflux 130 and Polysulfone 600, respectively. polysulfone P 1700 159-170 beta-2-microglobulin Homo sapiens 58-78 2650660-5 1989 Hemodialysis with polysulfone dialyzers caused significantly lower plasma levels of beta-2-microglobulin compared with polyamide or hemophane membranes despite significantly lower levels in the rinsing solutions. polysulfone P 1700 18-29 beta-2-microglobulin Homo sapiens 84-104 2682301-8 1989 Further investigation is necessary for the explanation of the presumed high beta 2M generation rate in the HDF with polysulfone membranes before recommendation of safe long-term use of such highly permeable membranes for prevention of amyloidosis risks in dialytic patients. polysulfone P 1700 116-127 beta-2-microglobulin Homo sapiens 76-83 11264774-9 2001 As such, beta(2)M removal with highly permeable biocompatible membranes such as polysulfone and polyacrylonitrile is relatively large. polysulfone P 1700 80-91 beta-2-microglobulin Homo sapiens 9-17 3055992-10 1988 Volume-controlled dialysis with high-flux membranes (polysulfone 0.65 m2 and polysulfone 1.25 m2) lowered beta 2m; clearance values, however, were significantly higher when these dialyzers were used in a hemodiafiltration procedure. polysulfone P 1700 53-64 beta-2-microglobulin Homo sapiens 106-113 3055992-10 1988 Volume-controlled dialysis with high-flux membranes (polysulfone 0.65 m2 and polysulfone 1.25 m2) lowered beta 2m; clearance values, however, were significantly higher when these dialyzers were used in a hemodiafiltration procedure. polysulfone P 1700 77-88 beta-2-microglobulin Homo sapiens 106-113 29186592-7 2018 In multivariable meta-regression analyses, we found significantly higher beta2M clearance for polyarylethersulfone dialyzers when used for HFD and polysulfone membranes in convective therapies. polysulfone P 1700 147-158 beta-2-microglobulin Homo sapiens 73-79 19621526-0 2009 [Effect of low-flux polysulphone membranes on the serum levels of inflammatory cytokines, C-reactive protein, lipoprotein (a), and beta2 microglobulin in hemodialysis patients]. polysulfone P 1700 20-32 beta-2-microglobulin Homo sapiens 131-150 14551370-9 2003 The mean plasma reduction rate of beta(2)m was 77 +/- 1% for DIAPES HF800 and polysulfone whereas it was 71 +/- 1% for polyamide (P < 0.05). polysulfone P 1700 78-89 beta-2-microglobulin Homo sapiens 34-42 14551370-10 2003 The mean beta(2)m amount removed and found in the haemodiafiltrate per session was 230 +/- 14 mg for DIAPES HF800, 186 +/- 13 mg for polysulfone and 147 +/- 13 mg for polyamide (P < 0.05 between each pair of membranes). polysulfone P 1700 133-144 beta-2-microglobulin Homo sapiens 9-17 14551370-13 2003 CONCLUSIONS: On-line HDF has shown to achieve plasma reduction rates for beta(2)m of up to 77% for the DIAPES HF800 membrane and for polysulfone. polysulfone P 1700 133-144 beta-2-microglobulin Homo sapiens 73-81 12164189-7 2002 Both membranes removed beta2 microglobulin during treatment (50.2% reduction with Polyflux and 54.5% reduction with polysulfone. polysulfone P 1700 116-127 beta-2-microglobulin Homo sapiens 23-42 3110692-6 1987 In contrast, beta 2m acutely decreased by 38.7% during a single session using polysulphone membranes and the steady state predialysis values were lower by 37.1% after two weeks intermittent haemodialysis with polysulphone membranes. polysulfone P 1700 78-90 beta-2-microglobulin Homo sapiens 13-20 3110692-6 1987 In contrast, beta 2m acutely decreased by 38.7% during a single session using polysulphone membranes and the steady state predialysis values were lower by 37.1% after two weeks intermittent haemodialysis with polysulphone membranes. polysulfone P 1700 209-221 beta-2-microglobulin Homo sapiens 13-20 14763499-4 2004 We hypothesized that discarding polysulfone dialyzers after the 25th rather than the 15th use would result in increased clearance of beta2-microglobulin (beta2MG) without clinically significant changes in small solute clearance or albumin loss. polysulfone P 1700 32-43 beta-2-microglobulin Homo sapiens 133-152 14763499-4 2004 We hypothesized that discarding polysulfone dialyzers after the 25th rather than the 15th use would result in increased clearance of beta2-microglobulin (beta2MG) without clinically significant changes in small solute clearance or albumin loss. polysulfone P 1700 32-43 beta-2-microglobulin Homo sapiens 154-161 14763499-13 2004 Reprocessing of polysulfone dialyzers with CAH 25 times significantly increased albumin loss and beta2MG clearance but did not appear to affect urea or creatinine clearance. polysulfone P 1700 16-27 beta-2-microglobulin Homo sapiens 97-104 9328364-6 1997 The reduction in plasma beta2-microglobulin concentration from predialysis to postdialysis was 30% for the first use of the dialyzer containing polysulfone membranes, but decreased significantly (P = 0.042) following reuse to 12% for the tenth use. polysulfone P 1700 144-155 beta-2-microglobulin Homo sapiens 24-43 10737167-13 2000 If one adds the known 17% adsorption on the polysulfone membrane, a total of 341.6 mg beta2-M per session is removed, which adds up to 1024.8 mg a week. polysulfone P 1700 44-55 beta-2-microglobulin Homo sapiens 86-93 10667721-3 2000 Plasma levels of beta2 microglobulin were reduced at the end of treatment with both membranes (49.8% of pretreatment values for Polyflux; 45.9%, Fresenius Polysulfone) and was associated with the recovery of 207 +/- 84 mg of beta2 microglobulin from the dialyzing fluid for Polyflux compared with 147 +/- 29 for Fresenius Polysulfone (p = 0.12). polysulfone P 1700 155-166 beta-2-microglobulin Homo sapiens 17-36 10499310-12 1999 This discrepancy seems to be due to an enhanced beta2-M adsorption to the polysulfone membrane during HDF. polysulfone P 1700 74-85 beta-2-microglobulin Homo sapiens 48-55 9569951-8 1998 CONCLUSION: HDF with an on-line replacement solution at 100 ml/min and a high-flux and biocompatible polysulphone membrane represents a new tool for enhanced removal of beta 2M. polysulfone P 1700 101-113 beta-2-microglobulin Homo sapiens 169-176 8793795-3 1996 Plasma levels of beta 2 microglobulin fell to 49.9% of pretreatment values by 210 min when using the Fresenius Polysulfone membrane, 60.2% with the Polyphen membrane, and 63.1% with the Biosulfane membrane. polysulfone P 1700 111-122 beta-2-microglobulin Homo sapiens 17-37 9347661-9 1997 CONCLUSION: polysulphone and polyacrylonitrile membrane induced significantly less beta-2 microglobulin production compared to cuprophane and slightly less compared to cellulose diacetate membrane. polysulfone P 1700 12-24 beta-2-microglobulin Homo sapiens 83-103 8887291-10 1996 There was a significant decrease in pre-dialysis plasma beta 2-microglobulin levels in high-flux dialysis of 9.04 +/- 10.46 mg/liter (23%) and in hemodiafiltration of 6.35 +/- 12.28 mg/liter (16%), both using high-flux polysulfone membrane in comparison with Cuprophan and low-flux polysulfone membranes (P = 0.032). polysulfone P 1700 219-230 beta-2-microglobulin Homo sapiens 56-76 8887291-10 1996 There was a significant decrease in pre-dialysis plasma beta 2-microglobulin levels in high-flux dialysis of 9.04 +/- 10.46 mg/liter (23%) and in hemodiafiltration of 6.35 +/- 12.28 mg/liter (16%), both using high-flux polysulfone membrane in comparison with Cuprophan and low-flux polysulfone membranes (P = 0.032). polysulfone P 1700 282-293 beta-2-microglobulin Homo sapiens 56-76 8955759-7 1996 Serum levels of beta 2-MG were significantly reduced in patients treated with high-flux polysulfone membranes. polysulfone P 1700 88-99 beta-2-microglobulin Homo sapiens 16-25 7858335-10 1994 Hemodiafiltration using a polysulfone membrane dialyzer raised delivered Kt/VUrea and reduced TACUrea and B2M levels significantly. polysulfone P 1700 26-37 beta-2-microglobulin Homo sapiens 106-109