PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11800023-15	2001	CONCLUSIONS: These results suggest that inhibition of hsp90 function, which causes depletion of hsp90 client proteins in tumor, contributes to the antitumor activity of KF58333, and that the stereochemistry of the oxime moiety is important for the biological activity of radicicol oxime derivatives.	Oximes	214-219	heat shock protein 90 alpha family class A member 1	Homo sapiens	54-59	
11749701-1	2001	A novel oxime derivative of radicicol, KF58333, binds to the heat shock protein 90 (Hsp90) and destabilizes its associated signaling molecules.	Oximes	8-13	heat shock protein 90 alpha family class A member 1	Homo sapiens	61-82	
11749701-1	2001	A novel oxime derivative of radicicol, KF58333, binds to the heat shock protein 90 (Hsp90) and destabilizes its associated signaling molecules.	Oximes	8-13	heat shock protein 90 alpha family class A member 1	Homo sapiens	84-89	
10979978-0	2000	Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G(1) phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex.	Oximes	6-11	heat shock protein 90 alpha family class A member 1	Homo sapiens	206-211	
34844036-0	2022	Novel O-acylated (E)-3-aryl-6,7-dihydrobenzisoxazol-4(5H)-one oximes targeting HSP90-HER2 axis in breast cancer cells.	Oximes	62-68	heat shock protein 90 alpha family class A member 1	Homo sapiens	79-84	
34844036-1	2022	Novel O-acylated (E)-3-aryl-6,7-dihydrobenzisoxazol-4(5H)-one oximes were designed as potential HSP90 inhibitors.	Oximes	62-68	heat shock protein 90 alpha family class A member 1	Homo sapiens	96-101