PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 5535753-0 1970 [Studies of general pharmacological actions of SL 396, beta-D-galactosidase (lactase), an enzyme necessary in digestion of disaccharide]. Disaccharides 123-135 lactase Homo sapiens 77-84 3155250-1 1988 The disaccharide lactose, the principal carbohydrate of animal milks, requires the enzyme lactase to split it to glucose and galactose. Disaccharides 4-16 lactase Homo sapiens 90-97 3094461-1 1986 The sequential changes in intestinal lactase activity of 40 neonates were measured indirectly from the differential uptake and excretion of lactose and the non-metabolisable disaccharide lactulose contained in formula feeds. Disaccharides 174-186 lactase Homo sapiens 37-44 30388735-3 2018 Lactose is currently a common disaccharide in human nutrition, both in breastfed infants and in adults, but its digestion requires a specialized enzyme called lactase. Disaccharides 30-42 lactase Homo sapiens 159-166 19869557-3 1929 The demonstration of the lactase and detection of the hexose products of its action constitute experimental evidence that hydrolysis of the disaccharide is the first step in the fermentation of lactose by colon bacilli. Disaccharides 140-152 lactase Homo sapiens 25-32 32560312-2 2020 Lactose is a common disaccharide found in dairy that requires lactase-phlorizin hydrolase (LPH) to break down into glucose and galactose. Disaccharides 20-32 lactase Homo sapiens 62-89 32560312-2 2020 Lactose is a common disaccharide found in dairy that requires lactase-phlorizin hydrolase (LPH) to break down into glucose and galactose. Disaccharides 20-32 lactase Homo sapiens 91-94 30462373-1 2018 Lactase is the enzyme responsible for the digestion of the disaccharide lactose, and deficiency in this enzyme causes the prevalent medical condition lactose intolerance. Disaccharides 59-71 lactase Homo sapiens 0-7 22807302-1 2013 Disaccharide intolerance is the inability to digest certain carbohydrates due to a lack of one or more intestinal disaccharidases (e.g., lactase, maltase, isomaltase and sucrase). Disaccharides 0-12 lactase Homo sapiens 137-144 28132945-1 2017 Lactose, the principle sugar in milk, is a disaccharide hydrolyzed by intestinal lactase into glucose and galactose, which are absorbed directly by diffusion in the intestine. Disaccharides 43-55 lactase Homo sapiens 81-88 15901356-7 2005 beta-glucosidase or beta-galactosidase (lactase/phloridzin hydrolase, LPH) and alpha-glucosidase (sucrase-isomaltase) had different pH-dependent activities for disaccharide conjugates. Disaccharides 160-172 lactase Homo sapiens 40-47 15901356-7 2005 beta-glucosidase or beta-galactosidase (lactase/phloridzin hydrolase, LPH) and alpha-glucosidase (sucrase-isomaltase) had different pH-dependent activities for disaccharide conjugates. Disaccharides 160-172 lactase Homo sapiens 70-73 8726284-2 1996 The digestion of disaccharides and some oligosaccharides is undertaken by a number of small intestinal brush border enzymes: sucrase-isomaltase, lactase phlorizinhydrolase, maltase-glycoamylase and trehalase. Disaccharides 17-30 lactase Homo sapiens 145-152 12556948-3 2002 It can be fermented within the large intestine in those people who have insufficient expression of lactase enzyme on the intestinal mucosa to ferment this disaccharide to its absorbable, simple hexose sugars: glucose and galactose. Disaccharides 155-167 lactase Homo sapiens 99-106 8425445-6 1993 Breath methane levels in lactose-intolerant subjects following a lactose load continued to increase, however, despite the coingestion of exogenous lactase in amounts calculated to result in complete hydrolysis of the disaccharide. Disaccharides 217-229 lactase Homo sapiens 147-154