PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10739244-7 2000 Together, the aromatic rings of the C-2 and C-3 side chains sandwich the indole ring of Trp60D contained in the thrombin S2 insertion loop defined by the sequence "Tyr-Pro-Pro-Trp." Tyrosine 164-167 complement C3 Homo sapiens 44-47 14561755-0 2003 A corresponding tyrosine residue in the C2/factor B type A domain is a hot spot in the decay acceleration of the complement C3 convertases. Tyrosine 16-24 complement C3 Homo sapiens 113-126 12871936-0 2003 Sulfation of tyrosine 174 in the human C3a receptor is essential for binding of C3a anaphylatoxin. Tyrosine 13-21 complement C3 Homo sapiens 39-42 12871936-0 2003 Sulfation of tyrosine 174 in the human C3a receptor is essential for binding of C3a anaphylatoxin. Tyrosine 13-21 complement C3 Homo sapiens 80-83 1654087-6 1991 The resonance of some aromatic protons, i.e., C-2H of two tryptophans, C-2H and C-4H of six histidines, and C-2,6H and C-3,5H of six tyrosine residues in CRP, were assigned by means of deuterium labeling and NOE measurements. Tyrosine 133-141 complement C3 Homo sapiens 119-125 7659097-6 1995 The stability of the C3b-Tyr complex was measured under physiological conditions (pH 7.4, 37 degrees C) and compared to the stability of other C3b complexes. Tyrosine 25-28 complement C3 Homo sapiens 21-24 7659097-7 1995 C3b-Tyr decayed 50% in 19 hr at 37 degrees C, but C3b bound to a Tyr-containing peptide was more stable, exhibiting a t1/2 of 53 hr. Tyrosine 4-7 complement C3 Homo sapiens 0-3 7659097-7 1995 C3b-Tyr decayed 50% in 19 hr at 37 degrees C, but C3b bound to a Tyr-containing peptide was more stable, exhibiting a t1/2 of 53 hr. Tyrosine 65-68 complement C3 Homo sapiens 50-53 7659097-10 1995 The present evidence demonstrates that Tyr residues are highly reactive and that the C3b-Tyr linkage is stable. Tyrosine 89-92 complement C3 Homo sapiens 85-88 10571781-6 1999 Intracellular tyrosine phosphorylation in response to C3a was evaluated by Western blotting and chemiluminescence. Tyrosine 14-22 complement C3 Homo sapiens 54-57 10571781-10 1999 Incubation of HK-2 cells with C3a led to an increase in intracellular inositol phosphate and to tyrosine phosphorylation of at least two proteins in a pertussis-toxin-sensitive fashion. Tyrosine 96-104 complement C3 Homo sapiens 30-33 8602875-3 1996 Activated C3b primarily forms ester bonds with hydroxyl groups of carbohydrates on complement activating surfaces, but it has also been shown to react with the hydroxyl group of tyrosine and with specific Ser and Thr residues on IgG and on complement protein C4b. Tyrosine 178-186 complement C3 Homo sapiens 10-13 7659097-2 1995 In this study we have examined the reactivity of metastable C3b with the third type of hydroxyl group present in proteins, tyrosine (Tyr). Tyrosine 123-131 complement C3 Homo sapiens 60-63 7659097-2 1995 In this study we have examined the reactivity of metastable C3b with the third type of hydroxyl group present in proteins, tyrosine (Tyr). Tyrosine 133-136 complement C3 Homo sapiens 60-63 7659097-3 1995 The results demonstrated that Tyr reacts with the thioester of metastable C3b and that this reactivity was 11-fold better than that of threonine, 47-fold better than serine and 50-fold better than the reactivity of carbohydrates. Tyrosine 30-33 complement C3 Homo sapiens 74-77 2587586-0 1989 Binding of human C3a and the synthetic nonapeptide C3a (tyr-70-77) to rat peritoneal mast cells. Tyrosine 56-59 complement C3 Homo sapiens 51-54 582801-2 1979 This paper descirbes biosynthetic labeling experiments on the conversion of tyrosine to the C2- and C3-proline units of anthramycin, tomaymycin, and sibiromycin. Tyrosine 76-84 complement C3 Homo sapiens 92-102 3501427-6 1987 The C3a molecule is known to consist of a core region that comprises segment Tyr-15-Tyr-59. Tyrosine 77-80 complement C3 Homo sapiens 4-7 3501427-6 1987 The C3a molecule is known to consist of a core region that comprises segment Tyr-15-Tyr-59. Tyrosine 84-87 complement C3 Homo sapiens 4-7 6232320-18 1984 Furthermore, we demonstrated that generation of C3b in the presence of 3H-tyrosine resulted in covalent binding of the tyrosine specifically to the C3 alpha" chain, indicating that the inhibition of solubilization may be due to the competition between tyrosine and immune complexes for the covalent binding of C3. Tyrosine 74-82 complement C3 Homo sapiens 48-51 6232320-18 1984 Furthermore, we demonstrated that generation of C3b in the presence of 3H-tyrosine resulted in covalent binding of the tyrosine specifically to the C3 alpha" chain, indicating that the inhibition of solubilization may be due to the competition between tyrosine and immune complexes for the covalent binding of C3. Tyrosine 74-82 complement C3 Homo sapiens 148-156 6232320-18 1984 Furthermore, we demonstrated that generation of C3b in the presence of 3H-tyrosine resulted in covalent binding of the tyrosine specifically to the C3 alpha" chain, indicating that the inhibition of solubilization may be due to the competition between tyrosine and immune complexes for the covalent binding of C3. Tyrosine 119-127 complement C3 Homo sapiens 48-51 6232320-18 1984 Furthermore, we demonstrated that generation of C3b in the presence of 3H-tyrosine resulted in covalent binding of the tyrosine specifically to the C3 alpha" chain, indicating that the inhibition of solubilization may be due to the competition between tyrosine and immune complexes for the covalent binding of C3. Tyrosine 119-127 complement C3 Homo sapiens 148-156 31888465-6 2019 We presented evidence that AF can bind to complement component 3 (C3) to regulate inflammation-related pathways involving Lck/Yes novel tyrosine kinase (Lyn), protein kinase B (Akt), nuclear factor-kappaB (NF-kappaB) and immune factors. Tyrosine 136-144 complement C3 Homo sapiens 66-68