PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8565226-1 1996 Monoclonal antibodies (mAbs) were raised against a peptide of the 10 C-terminal amino acids of human brain acetylcholinesterase (AChE): H-Tyr-Ser-Lys-Gln-Asp-Arg-Cys-Ser-Asp-Leu-OH. Tyrosine 138-141 acetylcholinesterase (Cartwright blood group) Homo sapiens 107-127 10602696-6 1999 Finally, we have also investigated the effect of replacing Phe300 in the Torpedo californica enzyme by Tyr, which is present in the human AChE. Tyrosine 103-106 acetylcholinesterase (Cartwright blood group) Homo sapiens 138-142 12498995-1 2002 OBJECTIVE: a) To evaluate acetylcholinesterase (AChE) activities in erythrocyte membranes from phenylketonuric (PKU) patients and controls and to correlate with their plasma phenylalanine (Phe), tyrosine (Tyr), alanine (Ala) and dopamine (DA) levels. Tyrosine 195-203 acetylcholinesterase (Cartwright blood group) Homo sapiens 26-46 12498995-1 2002 OBJECTIVE: a) To evaluate acetylcholinesterase (AChE) activities in erythrocyte membranes from phenylketonuric (PKU) patients and controls and to correlate with their plasma phenylalanine (Phe), tyrosine (Tyr), alanine (Ala) and dopamine (DA) levels. Tyrosine 195-203 acetylcholinesterase (Cartwright blood group) Homo sapiens 48-52 12498995-1 2002 OBJECTIVE: a) To evaluate acetylcholinesterase (AChE) activities in erythrocyte membranes from phenylketonuric (PKU) patients and controls and to correlate with their plasma phenylalanine (Phe), tyrosine (Tyr), alanine (Ala) and dopamine (DA) levels. Tyrosine 205-208 acetylcholinesterase (Cartwright blood group) Homo sapiens 26-46 12498995-1 2002 OBJECTIVE: a) To evaluate acetylcholinesterase (AChE) activities in erythrocyte membranes from phenylketonuric (PKU) patients and controls and to correlate with their plasma phenylalanine (Phe), tyrosine (Tyr), alanine (Ala) and dopamine (DA) levels. Tyrosine 205-208 acetylcholinesterase (Cartwright blood group) Homo sapiens 48-52 11904227-8 2002 Thus a single amino acid substitution in the pi-cation site, from the aromatic tyrosine of B. fasciatus AChE to the alanine of BuChE, caused AChE to behave like BuChE. Tyrosine 79-87 acetylcholinesterase (Cartwright blood group) Homo sapiens 104-108 11904227-8 2002 Thus a single amino acid substitution in the pi-cation site, from the aromatic tyrosine of B. fasciatus AChE to the alanine of BuChE, caused AChE to behave like BuChE. Tyrosine 79-87 acetylcholinesterase (Cartwright blood group) Homo sapiens 141-145 8565226-1 1996 Monoclonal antibodies (mAbs) were raised against a peptide of the 10 C-terminal amino acids of human brain acetylcholinesterase (AChE): H-Tyr-Ser-Lys-Gln-Asp-Arg-Cys-Ser-Asp-Leu-OH. Tyrosine 138-141 acetylcholinesterase (Cartwright blood group) Homo sapiens 129-133 7836436-0 1995 Contribution of aromatic moieties of tyrosine 133 and of the anionic subsite tryptophan 86 to catalytic efficiency and allosteric modulation of acetylcholinesterase. Tyrosine 37-45 acetylcholinesterase (Cartwright blood group) Homo sapiens 144-164 28785576-6 2017 The lowest predicted binding energy was -7.84 kcal/mol corresponding to H-bond between biperiden molecule and Tyr 341 residuum in protein structure of AChE. Tyrosine 110-113 acetylcholinesterase (Cartwright blood group) Homo sapiens 151-155 8349597-2 1993 Substrate specificity determinants of human acetylcholinesterase (HuAChE) were identified by combination of molecular modeling and kinetic studies with enzymes mutated in residues Trp-86, Trp-286, Phe-295, Phe-297, Tyr-337, and Phe-338. Tyrosine 215-218 acetylcholinesterase (Cartwright blood group) Homo sapiens 44-64 31325829-7 2019 The fluorescence quenching analysis of AChE demonstrated that NB and DNB interacted with both tryptophan (Trp) and tyrosine (Tyr) residues, whereas TNB interacted only with Trp. Tyrosine 115-123 acetylcholinesterase (Cartwright blood group) Homo sapiens 39-43 31325829-7 2019 The fluorescence quenching analysis of AChE demonstrated that NB and DNB interacted with both tryptophan (Trp) and tyrosine (Tyr) residues, whereas TNB interacted only with Trp. Tyrosine 125-128 acetylcholinesterase (Cartwright blood group) Homo sapiens 39-43 8145739-0 1994 Role of tyrosine 337 in the binding of huperzine A to the active site of human acetylcholinesterase. Tyrosine 8-16 acetylcholinesterase (Cartwright blood group) Homo sapiens 79-99 34773872-7 2022 Quantitative conformational analysis further confirmed the atomic-scale computational chemistry conclusions, and the perturbation of (S)-pyraclofos on the AChE"s ordered conformation was lower than that of (R)-pyraclofos, which is germane to the interaction energies of the crucial residues, e.g. Tyr-124, Tyr-337, Asp-74, Trp-86, and Tyr-119. Tyrosine 297-300 acetylcholinesterase (Cartwright blood group) Homo sapiens 155-159 34773872-7 2022 Quantitative conformational analysis further confirmed the atomic-scale computational chemistry conclusions, and the perturbation of (S)-pyraclofos on the AChE"s ordered conformation was lower than that of (R)-pyraclofos, which is germane to the interaction energies of the crucial residues, e.g. Tyr-124, Tyr-337, Asp-74, Trp-86, and Tyr-119. Tyrosine 306-309 acetylcholinesterase (Cartwright blood group) Homo sapiens 155-159 34773872-7 2022 Quantitative conformational analysis further confirmed the atomic-scale computational chemistry conclusions, and the perturbation of (S)-pyraclofos on the AChE"s ordered conformation was lower than that of (R)-pyraclofos, which is germane to the interaction energies of the crucial residues, e.g. Tyr-124, Tyr-337, Asp-74, Trp-86, and Tyr-119. Tyrosine 335-338 acetylcholinesterase (Cartwright blood group) Homo sapiens 155-159 24836068-8 2014 Thorough docking calculations of the seven most potent AChE inhibitors from the set, showed that the hydrogen bond can be formed between amide -NH- moiety of compounds and -OH group of Tyr 124. Tyrosine 185-188 acetylcholinesterase (Cartwright blood group) Homo sapiens 55-59 24652148-2 2014 Most often binding to serine, tyrosine, or threonine residues is described as being of relevance for toxicological effects (e.g., acetylcholinesterase and neuropathy target esterase) or as biomarkers for post-exposure analysis (verification, e.g., albumin and butyrylcholinesterase). Tyrosine 30-38 acetylcholinesterase (Cartwright blood group) Homo sapiens 130-150 23936743-2 2013 The phosphomotifs associated with amino acid and tyrosine binding motifs in AChE and BChE were known to be common. Tyrosine 49-57 acetylcholinesterase (Cartwright blood group) Homo sapiens 76-80