PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18710949-12	2008	Thus, while PKB-dependent p27 phosphorylation appears to increase cyclin D1-Cdk4-p27 assembly or stabilize these complexes in vitro, cyclin D1-Cdk4-p27 activation requires the tyrosine phosphorylation of p27.	Tyrosine	176-184	cyclin D1	Homo sapiens	133-142	
19911372-6	2010	In addition, the increased tyrosine phosphorylation level of beta-catenin was associated with the increased nuclear level of beta-catenin and downstream signaling molecules such as c-myc and cyclin D1 that were associated with cell proliferation.	Tyrosine	27-35	cyclin D1	Homo sapiens	191-200	
15890789-4	2005	Hyperexpression of FAK autophosphorylation site (Tyr-397) mutant (MT-FAK) reduced FAK phosphorylation at Tyr-397 in proliferating cells and was accompanied by reduction of cyclin D1 and increase of myogenin expression.	Tyrosine	105-108	cyclin D1	Homo sapiens	172-181	
17178895-6	2006	Furthermore, we show that Ron overexpression leads to receptor phosphorylation and is associated with elevated levels of tyrosine phosphorylated beta-catenin and the up-regulation of genes, including cyclin D1 and c-myc, which are associated with poor prognosis in patients with human breast cancers.	Tyrosine	121-129	cyclin D1	Homo sapiens	200-209	
16651438-4	2006	Consistent with the increased Fas/CD95 expression, a drastic decrease in the Tyr(705) phosphorylation of STAT3, a known negative regulator of Fas/CD95 transcription, was found within 20 minutes in the luteolin-treated cells, leading to down-regulation in the target gene products of STAT3, such as cyclin D1, survivin, Bcl-xL, and vascular endothelial growth factor.	Tyrosine	77-80	cyclin D1	Homo sapiens	298-307	
15890789-4	2005	Hyperexpression of FAK autophosphorylation site (Tyr-397) mutant (MT-FAK) reduced FAK phosphorylation at Tyr-397 in proliferating cells and was accompanied by reduction of cyclin D1 and increase of myogenin expression.	Tyrosine	49-52	cyclin D1	Homo sapiens	172-181	
17949810-8	2008	Tyrosine phosphorylation of beta-catenin was associated with its nuclear localization and enhanced transcription of target genes c-myc and cyclin D1.	Tyrosine	0-8	cyclin D1	Homo sapiens	139-148	
16314517-6	2005	We further show that the transcriptional regulation of cyclin D1 and cell cycle control by TFII-I are dependent on its tyrosine phosphorylation at positions 248 and 611, sites required for its growth signal-mediated transcriptional activity.	Tyrosine	119-127	cyclin D1	Homo sapiens	55-64	
21719533-6	2011	We show that mutation of PAK1 Tyr 153, 201, and 285 (sites of JAK2 phosphorylation; PAK1 Y3F) decreases both PAK1 nuclear translocation in response to PRL and PRL-induced cyclin D1 promoter activity by 55%.	Tyrosine	30-33	cyclin D1	Homo sapiens	171-180	
31831640-3	2019	We found that p27, when phosphorylated by tyrosine kinases, allosterically activated CDK4 in complex with cyclin D1 (CDK4-CycD1).	Tyrosine	42-50	cyclin D1	Homo sapiens	106-115	
31428968-0	2019	BCR-ABL induces tyrosine phosphorylation of YAP leading to expression of Survivin and Cyclin D1 in chronic myeloid leukemia cells.	Tyrosine	16-24	cyclin D1	Homo sapiens	86-95	
30498362-11	2018	Western blotting results revealed that FAM129B upregulated the expression of MMP2 and Cyclin D1 by enhancing the phosphorylation of FAK at Tyr 397 and Tyr 925.	Tyrosine	139-142	cyclin D1	Homo sapiens	86-95	
22746102-9	2013	These effects correlated with the reduction of vascular endothelial growth factor (VEGF), c-myc, and cyclin D1, and could be explained on the basis of inhibition of STAT3 tyrosine phosphorylation.	Tyrosine	171-179	cyclin D1	Homo sapiens	101-110	
8479754-0	1993	Two potentially oncogenic cyclins, cyclin A and cyclin D1, share common properties of subunit configuration, tyrosine phosphorylation and physical association with the Rb protein.	Tyrosine	109-117	cyclin D1	Homo sapiens	48-57	
8479754-6	1993	Moreover, cyclin D1 was found to be phosphorylated on tyrosine residues in vivo and, like cyclin A, was readily phosphorylated by pp60c-src in vitro.	Tyrosine	54-62	cyclin D1	Homo sapiens	10-19	
30498362-11	2018	Western blotting results revealed that FAM129B upregulated the expression of MMP2 and Cyclin D1 by enhancing the phosphorylation of FAK at Tyr 397 and Tyr 925.	Tyrosine	151-154	cyclin D1	Homo sapiens	86-95