PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16385629-5 2006 This effect depends on a tyrosine-based motif present in CD1 cytoplasmic tail as well as the actions of four Nef motifs, which are known to be involved in the down-regulation of MHC-I or CD4. Tyrosine 25-33 CD1c molecule Homo sapiens 57-60 10899914-4 2000 Deletion of the cytoplasmic tail of CD1c, containing a tyrosine-based internalization motif, abolished most of its intracellular localization. Tyrosine 55-63 CD1c molecule Homo sapiens 36-40