PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19487814-5 2009 Activation of eNOS in Cav1-/- lungs led to the impairment of PKG activity through tyrosine nitration. Tyrosine 82-90 protein kinase cGMP-dependent 1 Homo sapiens 61-64 20371672-8 2010 In vitro coincubation of recombinant human c-Src and PKG-Ialpha resulted in c-Src-mediated tyrosine phosphorylation of PKG-Ialpha and enhanced c-Src autophosphorylation/activation, suggesting that human c-Src directly tyrosine phosphorylates PKG-Ialpha and the c-Src/PKG-Ialpha interaction enhances Src kinase activity. Tyrosine 218-226 protein kinase cGMP-dependent 1 Homo sapiens 119-122 31519182-14 2019 PKA/PKG pathways inhibited EB-induced platelet aggregation and Akt phosphorylation but, surprisingly, enhanced Syk and LAT/PLCgamma2 tyrosine phosphorylation. Tyrosine 133-141 protein kinase cGMP-dependent 1 Homo sapiens 4-7 25586176-8 2015 These data indicated that TNF-alpha-induced repression of GKAP42 via cGK-Ialpha caused reduction of insulin-induced IRS-1 tyrosine phosphorylation at least in part. Tyrosine 122-130 protein kinase cGMP-dependent 1 Homo sapiens 69-79 20371672-7 2010 Furthermore, SFK activity contributed to endogenous tyrosine phosphorylation of PKG-Ialpha in OV2008 and A2780cp cells. Tyrosine 52-60 protein kinase cGMP-dependent 1 Homo sapiens 80-83 20371672-8 2010 In vitro coincubation of recombinant human c-Src and PKG-Ialpha resulted in c-Src-mediated tyrosine phosphorylation of PKG-Ialpha and enhanced c-Src autophosphorylation/activation, suggesting that human c-Src directly tyrosine phosphorylates PKG-Ialpha and the c-Src/PKG-Ialpha interaction enhances Src kinase activity. Tyrosine 91-99 protein kinase cGMP-dependent 1 Homo sapiens 53-56 20371672-8 2010 In vitro coincubation of recombinant human c-Src and PKG-Ialpha resulted in c-Src-mediated tyrosine phosphorylation of PKG-Ialpha and enhanced c-Src autophosphorylation/activation, suggesting that human c-Src directly tyrosine phosphorylates PKG-Ialpha and the c-Src/PKG-Ialpha interaction enhances Src kinase activity. Tyrosine 91-99 protein kinase cGMP-dependent 1 Homo sapiens 119-122 20371672-8 2010 In vitro coincubation of recombinant human c-Src and PKG-Ialpha resulted in c-Src-mediated tyrosine phosphorylation of PKG-Ialpha and enhanced c-Src autophosphorylation/activation, suggesting that human c-Src directly tyrosine phosphorylates PKG-Ialpha and the c-Src/PKG-Ialpha interaction enhances Src kinase activity. Tyrosine 91-99 protein kinase cGMP-dependent 1 Homo sapiens 119-122 20371672-8 2010 In vitro coincubation of recombinant human c-Src and PKG-Ialpha resulted in c-Src-mediated tyrosine phosphorylation of PKG-Ialpha and enhanced c-Src autophosphorylation/activation, suggesting that human c-Src directly tyrosine phosphorylates PKG-Ialpha and the c-Src/PKG-Ialpha interaction enhances Src kinase activity. Tyrosine 91-99 protein kinase cGMP-dependent 1 Homo sapiens 119-122 20371672-8 2010 In vitro coincubation of recombinant human c-Src and PKG-Ialpha resulted in c-Src-mediated tyrosine phosphorylation of PKG-Ialpha and enhanced c-Src autophosphorylation/activation, suggesting that human c-Src directly tyrosine phosphorylates PKG-Ialpha and the c-Src/PKG-Ialpha interaction enhances Src kinase activity. Tyrosine 218-226 protein kinase cGMP-dependent 1 Homo sapiens 53-56 20371672-8 2010 In vitro coincubation of recombinant human c-Src and PKG-Ialpha resulted in c-Src-mediated tyrosine phosphorylation of PKG-Ialpha and enhanced c-Src autophosphorylation/activation, suggesting that human c-Src directly tyrosine phosphorylates PKG-Ialpha and the c-Src/PKG-Ialpha interaction enhances Src kinase activity. Tyrosine 218-226 protein kinase cGMP-dependent 1 Homo sapiens 119-122 20371672-8 2010 In vitro coincubation of recombinant human c-Src and PKG-Ialpha resulted in c-Src-mediated tyrosine phosphorylation of PKG-Ialpha and enhanced c-Src autophosphorylation/activation, suggesting that human c-Src directly tyrosine phosphorylates PKG-Ialpha and the c-Src/PKG-Ialpha interaction enhances Src kinase activity. Tyrosine 218-226 protein kinase cGMP-dependent 1 Homo sapiens 119-122 19487814-8 2009 Together, these data show that loss of caveolin-1 leads to hyperactive eNOS and subsequent tyrosine nitration-dependent impairment of PKG activity, which results in PH. Tyrosine 91-99 protein kinase cGMP-dependent 1 Homo sapiens 134-137 17616649-3 2007 Hypoxia decreased the relaxation response to 8-bromo-cGMP, PKG protein expression, and kinase activity and increased tyrosine nitration in PKG. Tyrosine 117-125 protein kinase cGMP-dependent 1 Homo sapiens 139-142 9675253-3 1998 The kinase activity of cGK is elevated approximately 4-fold (relative to autophosphorylated cGK) or 10-fold (relative to unphosphorylated cGK) upon tyrosine phosphorylation by Src. Tyrosine 148-156 protein kinase cGMP-dependent 1 Homo sapiens 23-26 9675253-3 1998 The kinase activity of cGK is elevated approximately 4-fold (relative to autophosphorylated cGK) or 10-fold (relative to unphosphorylated cGK) upon tyrosine phosphorylation by Src. Tyrosine 148-156 protein kinase cGMP-dependent 1 Homo sapiens 92-95 9675253-3 1998 The kinase activity of cGK is elevated approximately 4-fold (relative to autophosphorylated cGK) or 10-fold (relative to unphosphorylated cGK) upon tyrosine phosphorylation by Src. Tyrosine 148-156 protein kinase cGMP-dependent 1 Homo sapiens 92-95