PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16037832-5 2005 The diagnosis of XHIGM was confirmed by the finding of CD40L expression < 1% of normal and a tyrosine 169 asparaginase (t526a) mutation in exon 5 (the tumor necrosis factor domain) of the CD40L gene. Tyrosine 93-101 CD40 ligand Homo sapiens 188-193 16186418-2 2005 Here, we show how CD40L increases vascular inflammation and thrombosis via tyrosine nitration and inhibition of prostacyclin synthase (PGIS), an enzyme with antithrombotic, antiproliferative, and dilatory functions in the normal vasculature. Tyrosine 75-83 CD40 ligand Homo sapiens 18-23 31479717-10 2019 WW + Tyr improved endothelial function, increased plasma HDL-cholesterol and antithrombin IIII, and decreased plasma homocysteine, endothelin 1, and CD40L, P65/RELA, and CFH gene expression in peripheral blood mononuclear cells (p < 0.05). Tyrosine 5-8 CD40 ligand Homo sapiens 149-154 15067037-5 2004 The tyrosine phosphorylation of CD28i followed the cross-linking of CD40L, and the overexpression of CD28i augmented the c-Jun NH2-terminal kinase, p21-activated kinase 2, and nuclear factor kappaB activation. Tyrosine 4-12 CD40 ligand Homo sapiens 68-73 9916733-7 1999 In B cells isolated from PBMC of AD patients with high serum IgE levels, JAK3 was constitutively phosphorylated at the tyrosine residue, and its phosphorylation was enhanced by the treatment with CD40L and/or IL-4 as was that in splenic B cells of NC/Nga mice with dermatitis and high IgE levels. Tyrosine 119-127 CD40 ligand Homo sapiens 196-201 7513724-10 1994 Neutralizing Abs directed against gp39 inhibited PMAct-induced protein tyrosine phosphorylation of B cell substrates. Tyrosine 71-79 CD40 ligand Homo sapiens 34-38 9345261-3 1997 Activation of T-lymphocytes via CD40L induces tyrosine phosphorylation of cellular proteins including PLC gamma. Tyrosine 46-54 CD40 ligand Homo sapiens 32-37 9345261-5 1997 Inhibition of src-like tyrosine kinases by Herbimycin A prevents these activation events suggesting a crucial role of tyrosine phosphorylation in T-lymphocyte activation via CD40L. Tyrosine 23-31 CD40 ligand Homo sapiens 174-179 30078020-9 2018 Capsid tyrosine-modified rAAV5-CD40L-M was packaged and carried out in vivo. Tyrosine 7-15 CD40 ligand Homo sapiens 31-38