PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23892456-7 2013 In Sox2, tyrosine to alanine mutations within a triple-repeat motif (S X T/S Y) abrogates the Nanog-Sox2 interaction, alters expression of genes associated with the Nanog-Sox2 cognate sequence, and reduces the ability of Sox2 to rescue ES cell differentiation induced by endogenous Sox2 deletion. Tyrosine 9-17 Nanog homeobox Homo sapiens 94-99 26890744-7 2016 In addition, we also found that miR-302-mediated Akt signaling further stimulates Nanog expression to suppress Abeta-induced p-Ser307 IRS-1 expression and thus enhances tyrosine phosphorylation and p-Ser 473-Akt/p-Ser 9-GSK3beta formation. Tyrosine 169-177 Nanog homeobox Homo sapiens 82-87 23892456-7 2013 In Sox2, tyrosine to alanine mutations within a triple-repeat motif (S X T/S Y) abrogates the Nanog-Sox2 interaction, alters expression of genes associated with the Nanog-Sox2 cognate sequence, and reduces the ability of Sox2 to rescue ES cell differentiation induced by endogenous Sox2 deletion. Tyrosine 9-17 Nanog homeobox Homo sapiens 165-170 23892456-8 2013 Substitution of the tyrosines with phenylalanine rescues both the Sox2-Nanog interaction and efficient self-renewal. Tyrosine 20-29 Nanog homeobox Homo sapiens 71-76 22493428-10 2012 The site-directed mutagenesis of Nanog tyrosines, Y35F and Y174F, blocked phosphorylation and binding by FAK. Tyrosine 39-48 Nanog homeobox Homo sapiens 33-38 21685938-4 2012 Our results indicate that HA binding to CD44 promotes Nanog-Stat-3 (also tyrosine phosphorylated Stat-3) complex formation, nuclear translocation and transcriptional activation. Tyrosine 73-81 Nanog homeobox Homo sapiens 54-59