PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19727814-9	2010	When wild type p53 expression was specifically inhibited by RNA-interference, A549 cells treated with MONCPT delayed the onset of G2/M arrest; meanwhile p-ERK and Cdc2 were up-regulated while p21 and CDK7 were down-regulated in A549 cells treated with MONCPT and p53 SiRNA transfection in contrast to cells treated with 100.0 nM MONCPT alone.	10-methoxy-9-nitrocamptothecin	102-108	cyclin dependent kinase 1	Homo sapiens	163-167	
20095141-8	2009	Moreover, MONCPT exposure (0.1 microM, 24 h) caused down-regulation of CDK7, p-Cdc2, and cyclinB1.	10-methoxy-9-nitrocamptothecin	10-16	cyclin dependent kinase 1	Homo sapiens	79-83