PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26879142-0 2016 Linoleic acid and stearic acid elicit opposite effects on AgRP expression and secretion via TLR4-dependent signaling pathways in immortalized hypothalamic N38 cells. stearic acid 18-30 toll-like receptor 4 Mus musculus 92-96 26879142-8 2016 In contrast, SA promoted TLR4 protein expression and activated TLR4-dependent inflammation pathway, with elevated ratio of p-JNK/JNK. stearic acid 13-15 toll-like receptor 4 Mus musculus 25-29 26879142-8 2016 In contrast, SA promoted TLR4 protein expression and activated TLR4-dependent inflammation pathway, with elevated ratio of p-JNK/JNK. stearic acid 13-15 toll-like receptor 4 Mus musculus 63-67 26879142-9 2016 While TLR4 siRNA reversed the stimulatory effects of SA on AgRP expression and TLR4-dependent inflammation. stearic acid 53-55 toll-like receptor 4 Mus musculus 6-10 26879142-9 2016 While TLR4 siRNA reversed the stimulatory effects of SA on AgRP expression and TLR4-dependent inflammation. stearic acid 53-55 toll-like receptor 4 Mus musculus 79-83 26879142-10 2016 Moreover, we found that TLR4 was also involved in LA-enhanced and SA-impaired leptin/insulin signal pathways in N38 cells. stearic acid 66-68 toll-like receptor 4 Mus musculus 24-28 26879142-11 2016 In conclusion, our findings indicated that LA elicited inhibitory while SA exerted stimulatory effects on AgRP expression and secretion via TLR4-dependent inflammation and leptin/insulin pathways in N38 cells. stearic acid 72-74 toll-like receptor 4 Mus musculus 140-144 22556332-0 2012 Stearic acid accumulation in macrophages induces toll-like receptor 4/2-independent inflammation leading to endoplasmic reticulum stress-mediated apoptosis. stearic acid 0-12 toll-like receptor 4 Mus musculus 49-69 22556332-6 2012 Intracellular stearic acid accumulation induces Toll-like receptor 4/2-independent inflammation that results in ER stress-mediated apoptosis of MPMs. stearic acid 14-26 toll-like receptor 4 Mus musculus 48-68