PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20101215-4 2010 We found that CD109 is produced as a 205 kDa glycoprotein, which is then processed in the Golgi apparatus into 180 kDa and 25 kDa proteins by furin (furinase). furinase 149-157 CD109 molecule Homo sapiens 14-19 20101215-6 2010 To investigate whether furinase cleavage of CD109 is necessary for its biological activity, we mutated arginine 1273 in the CD109 furinase cleavage motif (amino acid 1270-RRRR-1273) to serine (R1273S). furinase 23-31 CD109 molecule Homo sapiens 44-49 20101215-6 2010 To investigate whether furinase cleavage of CD109 is necessary for its biological activity, we mutated arginine 1273 in the CD109 furinase cleavage motif (amino acid 1270-RRRR-1273) to serine (R1273S). furinase 23-31 CD109 molecule Homo sapiens 124-129 20101215-6 2010 To investigate whether furinase cleavage of CD109 is necessary for its biological activity, we mutated arginine 1273 in the CD109 furinase cleavage motif (amino acid 1270-RRRR-1273) to serine (R1273S). furinase 130-138 CD109 molecule Homo sapiens 124-129