PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15951421-3	2005	Here, we show that in the spinal sensory circuit progesterone conversion into 5alpha-DHP and 3alpha,5alpha-THP is inhibited dose-dependently by substance P (SP), a major mediator of painful signals.	5-alpha-Dihydroprogesterone	78-88	tachykinin precursor 1	Homo sapiens	144-155	
15951421-3	2005	Here, we show that in the spinal sensory circuit progesterone conversion into 5alpha-DHP and 3alpha,5alpha-THP is inhibited dose-dependently by substance P (SP), a major mediator of painful signals.	5-alpha-Dihydroprogesterone	78-88	tachykinin precursor 1	Homo sapiens	157-159	
15951421-5	2005	Evidence for a potent inhibitory effect of SP on 5alpha-DHP and 3alpha,5alpha-THP formation in the SC was provided by combining pulse-chase experiments using [3H]progesterone as precursor, HPLC, recrystallization of [3H]metabolites to constant specific activity, and continuous flow detection of radioactive steroids.	5-alpha-Dihydroprogesterone	49-59	tachykinin precursor 1	Homo sapiens	43-45	
15951421-7	2005	The selective rNK1 antagonist SR140333 totally reversed the effect of SP on progesterone conversion into 5alpha-DHP and 3alpha,5alpha-THP.	5-alpha-Dihydroprogesterone	105-115	tachykinin precursor 1	Homo sapiens	70-72