PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16944117-3 2006 METHODS: We tested the hypothesis that 5-ASA represents a substrate of P-glycoprotein (P-gp) and/or multidrug resistance-associated protein 2 (MRP2), thereby possibly contributing to variable therapeutic effects. Mesalamine 39-44 ATP binding cassette subfamily B member 1 Homo sapiens 71-85 16944117-3 2006 METHODS: We tested the hypothesis that 5-ASA represents a substrate of P-glycoprotein (P-gp) and/or multidrug resistance-associated protein 2 (MRP2), thereby possibly contributing to variable therapeutic effects. Mesalamine 39-44 ATP binding cassette subfamily B member 1 Homo sapiens 87-91 16944117-6 2006 RESULTS: In Caco-2 cells a P-gp-mediated efflux of 5-ASA (5-500 muM) could be excluded. Mesalamine 51-56 ATP binding cassette subfamily B member 1 Homo sapiens 27-31