PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34462641-14 2021 The RIP1, RIP3, Drp1, IL-1beta, IL-18, and caspase-1 mRNA levels in the QYSX, 5-ASA, SX, and QY groups were significantly lower than those in the DSS group (P < 0.05), but there were no differences between the QYSX group and the 5-ASA group. Mesalamine 78-83 interleukin 1 alpha Mus musculus 22-30 34874516-10 2022 Meanwhile, HQD-H and 5-ASA significantly decreased the serum IL-1beta, IL-6 and TNF-alpha levels of mice (P<0.05). Mesalamine 21-26 interleukin 1 alpha Mus musculus 61-69 34059563-4 2021 Intrarectal treatment of moderate and severe colitis with 5-ASA alone or HA alone at a dose of 30 mg/kg led to a significant decrease in clinical activity and histology scores, myeloperoxidase activity (MPO), TNF-alpha, IL-6 and IL-1beta in colitis mice compared to untreated animals. Mesalamine 58-63 interleukin 1 alpha Mus musculus 229-237 33138176-8 2020 Intrarectal treatment of colitis with 30 mg/kg chitosan alone and with 30 mg/kg 5-ASA for 3 days led to a significant decrease in MPO, ALP, TNF-alpha, IL-6, IL-1beta and NF-kappaB in colitis mice compared to untreated mice. Mesalamine 80-85 interleukin 1 alpha Mus musculus 157-165