PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20197483-11 2010 Moreover, the presence of 5-ASA significantly reduced mutations in TGFBR2 (A10) and ACVR2 (A8) by 39.9% and 46.2%, respectively. Mesalamine 26-31 activin A receptor type 2A Homo sapiens 84-89 20197483-12 2010 CONCLUSIONS: 5-ASA increases replication fidelity in mononucleotide, dinucleotide, and tetranucleotide repeats and reduces mutations in tumor suppressor genes TGFBR2 and ACVR2, a finding that may provoke in vivo studies for the prevention of colorectal cancer in hereditary nonpolyposis colorectal cancer. Mesalamine 13-18 activin A receptor type 2A Homo sapiens 170-175