PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1358240-7	1992	By contrast, 5-aminosalicylic acid induced a threefold increase in the IL-8 release.	Mesalamine	13-34	C-X-C motif chemokine ligand 8	Homo sapiens	71-75	
17941093-12	2008	The IL-8 release is MAPK-dependent and inhibited by mesalamine.	Mesalamine	52-62	C-X-C motif chemokine ligand 8	Homo sapiens	4-8	
18473409-12	2008	CONCLUSION: In group A (oral NAC combined with mesalamine) contrarily to group B (mesalamine alone), the clinical improvement correlates with a decrease of chemokines such as MCP-1 and IL-8.	Mesalamine	47-57	C-X-C motif chemokine ligand 8	Homo sapiens	185-189	
17941093-0	2008	Characterization of epithelial IL-8 response to inflammatory bowel disease mucosal E. coli and its inhibition by mesalamine.	Mesalamine	113-123	C-X-C motif chemokine ligand 8	Homo sapiens	31-35	
17941093-9	2008	IL-8 release was mediated by extracellular-regulated kinase (ERK) and p38 mitogen-activated protein kinase (MAPK) and inhibited by mesalamine, but not hydrocortisone, at therapeutic concentrations.	Mesalamine	131-141	C-X-C motif chemokine ligand 8	Homo sapiens	0-4	
12519386-9	2003	Pharmacological inhibition of protein tyrosine phosphatases or treatment with mesalamine or sulphasalazine diminished IL-1 beta-stimulated IL-8 secretion by butyrate-exposed HT-29 cells substantially.	Mesalamine	78-88	C-X-C motif chemokine ligand 8	Homo sapiens	139-143	
8281849-6	1994	At the cellular level, 5-aminosalicylic acid inhibited phorbol myristate acetate (100 ng/ml)-activated superoxide generation to 82.3 +/- 9.3%, the formylmethionyl leucyl peptide (10(-5) M) to 61.0 +/- 6.8%, and the NaF (20 mM)-stimulated production to 32.3 +/- 3.2% (mean +/- SD, P < 0.01).	Mesalamine	23-44	C-X-C motif chemokine ligand 8	Homo sapiens	215-218	
30478770-7	2019	Multiple linear regression models predicted significant association between transcript levels of Ki-67, NF-kB (p65), PPARgamma, COX-2 and IL-8, CDC25A, and CXCL10 with duration of drug (5-ASA) exposure (P <= 0.05).	Mesalamine	186-191	C-X-C motif chemokine ligand 8	Homo sapiens	138-142	
30630805-1	2018	Present investigation is conducted to investigate the clinical efficacy of mesalazine in combination with the Bifid Triple Viable Capsules on the ulcerative colitis (UC) and the resultant effect on the inflammatory factors (TNF-alpha, IL-8 and IL-10) of UC patients.	Mesalamine	75-85	C-X-C motif chemokine ligand 8	Homo sapiens	235-239	
26665398-0	2015	THE EFFECT OF SULFASALAZINE AND 5-AMINOSALICYLIC ACID ON THE SECRETION OF INTERLEUKIN 8 BY HUMAN COLON MYOFIBROBLASTS.	Mesalamine	32-53	C-X-C motif chemokine ligand 8	Homo sapiens	74-87