PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29550533-1 2018 Three new series of 5-aminosalicylic acid derivatives; series I (14, 16-18), series II (19-30) and series III (31-41) were synthesized as potential dual COX-2/5-LOX inhibitors. Mesalamine 20-41 arachidonate 5-lipoxygenase Homo sapiens 159-164 20948062-1 1996 Mesalazine- a 5 lipoxygenase inhibitor was tried in this open trial on 20 psoriatics. Mesalamine 0-10 arachidonate 5-lipoxygenase Homo sapiens 14-28 11430933-5 2001 Sulfasalazine and 5-aminosalicylic acid, therapeutic drugs for inflammatory bowel disease, inhibited 5-lipoxygenase activity with an IC(50) of 293 and 970 microM, respectively. Mesalamine 18-39 arachidonate 5-lipoxygenase Homo sapiens 101-115 2882965-0 1987 Inhibition of 5-lipoxygenase pathway of arachidonic acid metabolism in human neutrophils by sulfasalazine and 5-aminosalicylic acid. Mesalamine 110-131 arachidonate 5-lipoxygenase Homo sapiens 14-28