PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14742690-3 2004 This induction was especially pronounced when cells were treated with interleukin-1alpha (IL-1) plus aspirin for 24 h. Sodium salicylate, a poor COX inhibitor, likewise enhanced IL-1-mediated COX-2 gene expression whereas 5-aminosalicylic acid (5-ASA) or indomethacin had no effect. Mesalamine 222-243 interleukin 1 alpha Homo sapiens 70-88 14742690-3 2004 This induction was especially pronounced when cells were treated with interleukin-1alpha (IL-1) plus aspirin for 24 h. Sodium salicylate, a poor COX inhibitor, likewise enhanced IL-1-mediated COX-2 gene expression whereas 5-aminosalicylic acid (5-ASA) or indomethacin had no effect. Mesalamine 245-250 interleukin 1 alpha Homo sapiens 70-88 34259316-8 2021 Compared with those in the DSS group, the expressions of IL-1beta, IL-6, IL-17, and TNF-alpha in the DSS+DHA and DSS+5-aminosalicylic acid (5-ASA) groups were decreased, while the expressions of IL-4 and IL-10 were significantly upregulated. Mesalamine 117-138 interleukin 1 alpha Homo sapiens 57-65 33793375-2 2021 As mesalazine (5-ASA) could be involved in ER stress, proinflammatory and ER stress-associated cytokines and markers were measured.Results: Mesalazine (5-ASA) suppressed IL-6 mRNA in healthy donors and in HLA-B27+ and HLA-B27- patients but did not lead to induction and secretion of IL-1beta. Mesalamine 140-150 interleukin 1 alpha Homo sapiens 283-291 33793375-2 2021 As mesalazine (5-ASA) could be involved in ER stress, proinflammatory and ER stress-associated cytokines and markers were measured.Results: Mesalazine (5-ASA) suppressed IL-6 mRNA in healthy donors and in HLA-B27+ and HLA-B27- patients but did not lead to induction and secretion of IL-1beta. Mesalamine 152-157 interleukin 1 alpha Homo sapiens 283-291