PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34913070-11 2022 In addition, the results showed that 5-ASA attenuated the upregulation of transforming growth factor-beta1 and phosphorylated-SMAD3, and the reduction of peroxisome proliferator activated receptor gamma induced by PQ in lung tissue of rats and human lung fibroblast WI-38 VA13 cells. Mesalamine 37-42 peroxisome proliferator-activated receptor gamma Rattus norvegicus 154-202 18077625-6 2008 5-ASA treatment normalized both PPARgamma and RXRalpha expression at 3 days postirradiation and PPARalpha at 7 days. Mesalamine 0-5 peroxisome proliferator-activated receptor gamma Rattus norvegicus 32-41 25445696-15 2015 Furthermore, real-time PCR analysis indicated increased activation of the target receptor PPAR-gamma and the HMGCS2 gene in rats upon administration of 5-ASA loaded Nutriose:EC- and peas starch:EC pellets compared to the commercial product. Mesalamine 152-157 peroxisome proliferator-activated receptor gamma Rattus norvegicus 90-100 22841543-12 2013 The dual therapy n-3 PUFA plus 5-ASA also inhibited inflammatory response by lowering NF-kappaB activation (P<.01) or inducing peroxisome proliferator-activated receptor-gamma (PPARgamma) expression (P<.05). Mesalamine 31-36 peroxisome proliferator-activated receptor gamma Rattus norvegicus 130-178 22841543-12 2013 The dual therapy n-3 PUFA plus 5-ASA also inhibited inflammatory response by lowering NF-kappaB activation (P<.01) or inducing peroxisome proliferator-activated receptor-gamma (PPARgamma) expression (P<.05). Mesalamine 31-36 peroxisome proliferator-activated receptor gamma Rattus norvegicus 180-189 22841543-13 2013 These results indicate that 5-ASA plus n-3 PUFAs are more effective than a higher dose of 5-ASA alone to reduce NF-kappaB activation and to induce PPARgamma. Mesalamine 28-33 peroxisome proliferator-activated receptor gamma Rattus norvegicus 147-156 22841543-13 2013 These results indicate that 5-ASA plus n-3 PUFAs are more effective than a higher dose of 5-ASA alone to reduce NF-kappaB activation and to induce PPARgamma. Mesalamine 90-95 peroxisome proliferator-activated receptor gamma Rattus norvegicus 147-156