PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34913070-11	2022	In addition, the results showed that 5-ASA attenuated the upregulation of transforming growth factor-beta1 and phosphorylated-SMAD3, and the reduction of peroxisome proliferator activated receptor gamma induced by PQ in lung tissue of rats and human lung fibroblast WI-38 VA13 cells.	Mesalamine	37-42	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	154-202	
18077625-6	2008	5-ASA treatment normalized both PPARgamma and RXRalpha expression at 3 days postirradiation and PPARalpha at 7 days.	Mesalamine	0-5	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	32-41	
25445696-15	2015	Furthermore, real-time PCR analysis indicated increased activation of the target receptor PPAR-gamma and the HMGCS2 gene in rats upon administration of 5-ASA loaded Nutriose:EC- and peas starch:EC pellets compared to the commercial product.	Mesalamine	152-157	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	90-100	
22841543-12	2013	The dual therapy n-3 PUFA plus 5-ASA also inhibited inflammatory response by lowering NF-kappaB activation (P<.01) or inducing peroxisome proliferator-activated receptor-gamma (PPARgamma) expression (P<.05).	Mesalamine	31-36	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	130-178	
22841543-12	2013	The dual therapy n-3 PUFA plus 5-ASA also inhibited inflammatory response by lowering NF-kappaB activation (P<.01) or inducing peroxisome proliferator-activated receptor-gamma (PPARgamma) expression (P<.05).	Mesalamine	31-36	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	180-189	
22841543-13	2013	These results indicate that 5-ASA plus n-3 PUFAs are more effective than a higher dose of 5-ASA alone to reduce NF-kappaB activation and to induce PPARgamma.	Mesalamine	28-33	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	147-156	
22841543-13	2013	These results indicate that 5-ASA plus n-3 PUFAs are more effective than a higher dose of 5-ASA alone to reduce NF-kappaB activation and to induce PPARgamma.	Mesalamine	90-95	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	147-156