PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22493349-0 2012 5-aminosalicylic acid mediates expression of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase to suppress colorectal tumorigenesis. Mesalamine 0-21 hydroxyprostaglandin dehydrogenase 15 (NAD) Mus musculus 66-103 22493349-3 2012 Here we determined the effect of 5-aminosalicylic acid (5-ASA) on COX-2 and 15-PGDH expression and investigated its preventive effect for colorectal cancer (CRC). Mesalamine 33-54 hydroxyprostaglandin dehydrogenase 15 (NAD) Mus musculus 76-83 22493349-3 2012 Here we determined the effect of 5-aminosalicylic acid (5-ASA) on COX-2 and 15-PGDH expression and investigated its preventive effect for colorectal cancer (CRC). Mesalamine 56-61 hydroxyprostaglandin dehydrogenase 15 (NAD) Mus musculus 76-83 22493349-10 2012 CONCLUSION: 5-ASA exerts a preventive effect against colorectal tumor development through mediation of COX-2 and 15-PGDH expression. Mesalamine 12-17 hydroxyprostaglandin dehydrogenase 15 (NAD) Mus musculus 113-120