PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8575046-6	1995	Simultaneously, VIP also diminished or abolished the associated generation of arachidonate products.	Arachidonic Acid	78-90	vasoactive intestinal peptide	Rattus norvegicus	16-19	
8580482-6	1995	Simultaneously, VIP also diminished or abolished the associated generation of arachidonate products.	Arachidonic Acid	78-90	vasoactive intestinal peptide	Rattus norvegicus	16-19	
7475904-3	1995	In this study, we determined whether VIP increases the liberation of arachidonate from anterior pituitary cells.	Arachidonic Acid	69-81	vasoactive intestinal peptide	Rattus norvegicus	37-40	
7475904-8	1995	VIP (500 nM) significantly increased [3H] arachidonate liberation from primary cultures of anterior pituitary cells at 30 min (p < 0.5) and 60 min (p < 0.01), but had no significant effect on the liberation of this fatty acid at 15 or 120 min.	Arachidonic Acid	42-54	vasoactive intestinal peptide	Rattus norvegicus	0-3	
7475904-10	1995	VIP (60 min exposure) at concentrations of 100 and 500 nM significantly increased PRL release and arachidonate liberation in a concentration-dependent manner.	Arachidonic Acid	98-110	vasoactive intestinal peptide	Rattus norvegicus	0-3	
7475904-11	1995	Similarly, VIP increased [3H] arachidonate liberation from a preparation of anterior pituitary cells enriched in lactotropes.	Arachidonic Acid	30-42	vasoactive intestinal peptide	Rattus norvegicus	11-14	
1337377-2	1992	Treating cells with 0.1 mM arachidonic acid for 15 min at 37 degrees C increased the affinity of VIP receptors and the potency of the neuropeptide (up to five times) in the formation of cyclic AMP at maturity, but not at puberty.	Arachidonic Acid	27-43	vasoactive intestinal peptide	Rattus norvegicus	97-100	
1337377-5	1992	These results are compatible with the existence of a particular lipidic microdomain surrounding the VIP receptor in the cell membrane that would be altered by exposure to arachidonic acid (either directly or through conversion of arachidonic acid to its metabolites, as suggested by experiments on inhibition of the arachidonic acid cascade).	Arachidonic Acid	171-187	vasoactive intestinal peptide	Rattus norvegicus	100-103	
1337377-5	1992	These results are compatible with the existence of a particular lipidic microdomain surrounding the VIP receptor in the cell membrane that would be altered by exposure to arachidonic acid (either directly or through conversion of arachidonic acid to its metabolites, as suggested by experiments on inhibition of the arachidonic acid cascade).	Arachidonic Acid	230-246	vasoactive intestinal peptide	Rattus norvegicus	100-103	
1337377-5	1992	These results are compatible with the existence of a particular lipidic microdomain surrounding the VIP receptor in the cell membrane that would be altered by exposure to arachidonic acid (either directly or through conversion of arachidonic acid to its metabolites, as suggested by experiments on inhibition of the arachidonic acid cascade).	Arachidonic Acid	230-246	vasoactive intestinal peptide	Rattus norvegicus	100-103	
3748848-2	1986	VIP-induced vasodilation is independent of adrenergic or cholinergic receptors and, for the most part, of arachidonate metabolites, but its mechanism is still unknown.	Arachidonic Acid	106-118	vasoactive intestinal peptide	Rattus norvegicus	0-3	
1655977-1	1991	In the rat pineal gland, alpha 1-adrenergic agonists, which stimulate arachidonic acid release, also potentiate vasoactive intestinal peptide (VIP)- or beta-adrenergic-stimulated cyclic AMP (cAMP) and cyclic GMP (cGMP) accumulation.	Arachidonic Acid	70-86	vasoactive intestinal peptide	Rattus norvegicus	143-146	
1655977-9	1991	Taken together, these findings indicate that the arachidonic acid cascade is likely involved in the alpha 1-adrenergic potentiation of VIP- or beta-adrenergic-stimulated cAMP and cGMP accumulation.	Arachidonic Acid	49-65	vasoactive intestinal peptide	Rattus norvegicus	135-138	
1655977-10	1991	However, the specific arachidonic acid metabolite involved in the potentiation mechanisms of VIP- versus beta-adrenergic-stimulated cyclic nucleotide responses may be different.	Arachidonic Acid	22-38	vasoactive intestinal peptide	Rattus norvegicus	93-96	
2382732-4	1990	Simultaneously, VIP also diminished or abolished the associated generation of arachidonate products.	Arachidonic Acid	78-90	vasoactive intestinal peptide	Rattus norvegicus	16-19	
3039374-7	1987	Here we report that the alpha 1-adrenergic potentiation of the increases in cAMP elicited by VIP involves the formation of arachidonic acid metabolites and is mimicked by prostglandins F2 alpha and E2.	Arachidonic Acid	123-139	vasoactive intestinal peptide	Rattus norvegicus	93-96