PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31415760-7	2019	Inhibition of either p38-MAPK or NF-kappaB using specific inhibitors (SB203580, SB202190 or Bay11-7082, pyrrolidinedithiocarbamate) attenuated PA-induced downregulation of KCa2.3 and inhibition of p38-MAPK also attenuated PA-induced phosphorylation of NF-kappaB p65.	Palmitic Acid	143-145	mitogen-activated protein kinase 14	Homo sapiens	21-24	
32199904-6	2020	Furthermore, palmitic acid and chloroquine exposure significantly increased reactive oxygen species (ROS) and activated p38 and c-Jun N-terminal kinase (JNK).	Palmitic Acid	13-26	mitogen-activated protein kinase 14	Homo sapiens	120-123	
32062019-7	2020	Our findings suggest that high glucose and PA could induce excessive ER stress and apoptosis via promoting the overexpression of GLUT3 and FATP1, and ER stress could suppress BDNF and SYN expression through negatively regulating p38/ERK-CREB pathway and positively regulating NLRP3-IL-1beta pathway, which could be reversed by activated Nrf2-HO-1 pathway.	Palmitic Acid	43-45	mitogen-activated protein kinase 14	Homo sapiens	229-232	
31415760-7	2019	Inhibition of either p38-MAPK or NF-kappaB using specific inhibitors (SB203580, SB202190 or Bay11-7082, pyrrolidinedithiocarbamate) attenuated PA-induced downregulation of KCa2.3 and inhibition of p38-MAPK also attenuated PA-induced phosphorylation of NF-kappaB p65.	Palmitic Acid	143-145	mitogen-activated protein kinase 14	Homo sapiens	197-200	
31415760-7	2019	Inhibition of either p38-MAPK or NF-kappaB using specific inhibitors (SB203580, SB202190 or Bay11-7082, pyrrolidinedithiocarbamate) attenuated PA-induced downregulation of KCa2.3 and inhibition of p38-MAPK also attenuated PA-induced phosphorylation of NF-kappaB p65.	Palmitic Acid	222-224	mitogen-activated protein kinase 14	Homo sapiens	21-24	
31415760-8	2019	Furthermore, DPI reversed the increment of phospho-p38-MAPK by PA.	Palmitic Acid	63-65	mitogen-activated protein kinase 14	Homo sapiens	51-54	
31415760-9	2019	These results demonstrated that PA downregulated KCa2.3 expressions via Nox/ROS/p38-MAPK/NF-kappaB signaling leading to endothelial vasodilatory dysfunction.	Palmitic Acid	32-34	mitogen-activated protein kinase 14	Homo sapiens	80-83	
16873694-8	2006	The p38 target transcriptional factor activating transcription factor (ATF)-2 bound to the PTEN promoter, which was increased by palmitic acid treatment.	Palmitic Acid	129-142	mitogen-activated protein kinase 14	Homo sapiens	4-7	
31357761-7	2019	Results: Palmitic acid increased the phosphorylation of p38 MAPK and JNK in HepG2 cells (P< 0.05).	Palmitic Acid	9-22	mitogen-activated protein kinase 14	Homo sapiens	56-59	
21437903-4	2012	PA treatment provoked release of cytochrome c from the inner mitochondrial membrane to the cytosol, activated members of the MAPK protein family JNK, p38, ERK, activated caspases 3/9, and increased oxidative/nitrosative stress.	Palmitic Acid	0-2	mitogen-activated protein kinase 14	Homo sapiens	150-153	
18625049-6	2008	Using antibody-based protein microarray, we found that TXL attenuated PA-induced activation of p38-MAPK stress pathway.	Palmitic Acid	70-72	mitogen-activated protein kinase 14	Homo sapiens	95-98	
31357761-13	2019	Glucagon-like peptide-1 analogue, liraglutide may improve lipotoxicity of palmitic acid by mediating p38 MAPK and JNK pathways.	Palmitic Acid	74-87	mitogen-activated protein kinase 14	Homo sapiens	101-104	
30879166-0	2019	Activator protein-1 and caspase 8 mediate p38alpha MAPK-dependent cardiomyocyte apoptosis induced by palmitic acid.	Palmitic Acid	101-114	mitogen-activated protein kinase 14	Homo sapiens	42-45	
30879166-3	2019	Although we have previously shown that palmitic acid (PA), a saturated fatty acid (SFA) elevated in plasma of type 2 diabetes mellitus and morbid obesity, induces apoptosis in cardiomyocytes via p38alpha MAPK-dependent signaling, the downstream cascade events that cause cell death remain unknown.	Palmitic Acid	39-52	mitogen-activated protein kinase 14	Homo sapiens	195-203	
30879166-3	2019	Although we have previously shown that palmitic acid (PA), a saturated fatty acid (SFA) elevated in plasma of type 2 diabetes mellitus and morbid obesity, induces apoptosis in cardiomyocytes via p38alpha MAPK-dependent signaling, the downstream cascade events that cause cell death remain unknown.	Palmitic Acid	54-56	mitogen-activated protein kinase 14	Homo sapiens	195-203	
29792849-8	2018	These results demonstrate for the first time that PA upregulates KCa3.1 channels through TLR2/4, p38-MAPK and NF-kappaB pathway to promote the expression of MCP-1, and then induce the trans-endothelial migration of monocytes.	Palmitic Acid	50-52	mitogen-activated protein kinase 14	Homo sapiens	97-100	
24973767-4	2014	CM from palmitic acid-treated J774s (palm-mac-CM) impaired insulin signalling and insulin-stimulated glycogen synthesis, reduced Inhibitor kappaBalpha and increased phosphorylation of p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase in myotubes.	Palmitic Acid	8-21	mitogen-activated protein kinase 14	Homo sapiens	184-220	
16873694-10	2006	Palmitic acid inhibits insulin signaling by promoting PTEN activity and its transcription through p38 and its downstream transcription factor ATF-2.	Palmitic Acid	0-13	mitogen-activated protein kinase 14	Homo sapiens	98-101