PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22866302-5 2012 Palmitic acid enhanced binding activity of all centers, though to a different degree: if the palmitic acid/albumin proportion increased to 2-3, the probe binding to type 1 centers (located in the drug center I region) increased 1.5 times, while binding to type 3 centers increased more than 3-fold. Palmitic Acid 0-13 albumin Homo sapiens 107-114 25436195-0 2014 Interaction of palmitic Acid with metoprolol succinate at the binding sites of bovine serum albumin. Palmitic Acid 15-28 albumin Homo sapiens 86-99 25436195-2 2014 METHODS: The binding of metoprolol succinate to bovine serum albumin (BSA) was studied by equilibrium dialysis method (ED) at 27 C and pH 7.4, in order to have an insight in the binding chemistry of the drug to BSA in presence and absence of palmitic acid. Palmitic Acid 242-255 albumin Homo sapiens 55-68 22866302-5 2012 Palmitic acid enhanced binding activity of all centers, though to a different degree: if the palmitic acid/albumin proportion increased to 2-3, the probe binding to type 1 centers (located in the drug center I region) increased 1.5 times, while binding to type 3 centers increased more than 3-fold. Palmitic Acid 93-106 albumin Homo sapiens 107-114 33762794-5 2020 Cells were exposed to perfluorobutanesulfonic acid with or without 300 mumol/L fatty acid mixture (oleic acid:palmitic acid = 2:1) conjugated by bovine serum albumin as an inducer of steatosis for 48 hours. Palmitic Acid 110-123 albumin Homo sapiens 152-165 12044178-3 2002 FRET analysis showed that low concentration of palmitic acid (5 microM) increased the interdomain distance between the Trp-214 in domain II and CM-Cys-34 in domain I by approximately 5 A without perturbing the secondary structure of HSA and the immediate environment of Trp-214. Palmitic Acid 47-60 albumin Homo sapiens 233-236 8453960-2 1993 The binding affinity of warfarin was markedly increased on adding palmitic acid up to palmitate 4 mol per mol albumin and then it decreased. Palmitic Acid 66-79 albumin Homo sapiens 110-117 638175-8 1978 Studies with lauric, myristic, and palmitic acid showed that the decrease of binding affinity for progesterone was proportional to the amount of fatty acid added to albumin, and to its chain length. Palmitic Acid 35-48 albumin Homo sapiens 165-172 35058728-5 2022 Human primary astrocytes and SH-SY5Y cells were treated with palmitic acid conjugated Bovine Serum Albumin, and the effects of SGB121 were determined by MTT and lipid uptake assays. Palmitic Acid 61-74 albumin Homo sapiens 93-106 6960927-1 1982 Radioactively-labelled palmitic acid was used to study the effects of albumin, low temperature and several inhibitors of metabolism on transport of fatty acids into cultured human leukemic myeloid cells. Palmitic Acid 23-36 albumin Homo sapiens 70-77 467465-3 1979 Palmitic acid and some acidic drugs, warfarin and phenylbutazone added to human serum albumin, decreased phenytoin binding in a non competitive way. Palmitic Acid 0-13 albumin Homo sapiens 80-93 209828-0 1978 [Binding of spin-labeled palmitic acid by bovine serum albumin]. Palmitic Acid 25-38 albumin Homo sapiens 55-62 209828-1 1978 Investigation of the binding of spin-labeled palmitic acid and its esters with bovine serum albumin is presented. Palmitic Acid 45-58 albumin Homo sapiens 86-99 33951465-3 2021 Here, we report that KIM-1 mediates PT uptake of palmitic acid (PA)-bound albumin, leading to enhanced tubule injury with DNA damage, PT cell-cycle arrest, interstitial inflammation and fibrosis, and secondary glomerulosclerosis. Palmitic Acid 49-62 albumin Homo sapiens 74-81 164444-2 1975 Three spin-labeled derivatives of stearic acid and two derivatives of palmitic acid have been used to study the structure of the strong fatty acid binding site of bovine serum albumin. Palmitic Acid 70-83 albumin Homo sapiens 170-183 33951465-3 2021 Here, we report that KIM-1 mediates PT uptake of palmitic acid (PA)-bound albumin, leading to enhanced tubule injury with DNA damage, PT cell-cycle arrest, interstitial inflammation and fibrosis, and secondary glomerulosclerosis. Palmitic Acid 64-66 albumin Homo sapiens 74-81 30108828-7 2017 Palmitic acid has a strong binding affinity with human serum albumin (HSA), which has the ability to form non-covalent host-guest complexes and has a blood half-life of 19 days. Palmitic Acid 0-13 albumin Homo sapiens 55-68 29658532-9 2018 METHODS: Fourier transform infrared spectroscopy was applied to study changes of bovine serum albumin (as an analogue of human serum albumin) -helical structures after binding palmitic acid in a range of 0-20 palmitic acid: albumin molar ratios representing pure protein, partial, full saturation and excess binding sites capacity. Palmitic Acid 177-190 albumin Homo sapiens 88-101 29658532-9 2018 METHODS: Fourier transform infrared spectroscopy was applied to study changes of bovine serum albumin (as an analogue of human serum albumin) -helical structures after binding palmitic acid in a range of 0-20 palmitic acid: albumin molar ratios representing pure protein, partial, full saturation and excess binding sites capacity. Palmitic Acid 177-190 albumin Homo sapiens 127-140 29658532-9 2018 METHODS: Fourier transform infrared spectroscopy was applied to study changes of bovine serum albumin (as an analogue of human serum albumin) -helical structures after binding palmitic acid in a range of 0-20 palmitic acid: albumin molar ratios representing pure protein, partial, full saturation and excess binding sites capacity. Palmitic Acid 210-223 albumin Homo sapiens 88-101 29658532-10 2018 RESULTS: Amount of -helices was increasing along with the amount of palmitic acid: bovine serum albumin molar ratio and reached maximum value around 2 mol/mol. Palmitic Acid 69-82 albumin Homo sapiens 91-104 29658532-12 2018 Palmitic acid binding in two high-affinity sites leads to major structural changes, filling another sites only slightly influenced bovine serum albumin secondary structure. Palmitic Acid 0-13 albumin Homo sapiens 138-151 28414449-0 2017 Time-Dependent pH Scanning of the Acid-Induced Unfolding of Human Serum Albumin Reveals Stabilization of the Native Form by Palmitic Acid Binding. Palmitic Acid 124-137 albumin Homo sapiens 72-79 31694323-0 2019 Conformation and Aggregation of Human Serum Albumin in the Presence of Green Tea Polyphenol (EGCg) and/or Palmitic Acid. Palmitic Acid 106-119 albumin Homo sapiens 38-51