PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32272739-1 2020 A new pathway leading to the n-10 fatty acid series has been recently evidenced, starting from sapienic acid, a monounsaturated fatty acid (MUFA) resulting from the transformation of palmitic acid by delta-6 desaturase. Palmitic Acid 183-196 fatty acid desaturase 2 Homo sapiens 200-218 29750879-4 2018 The study examines whether challenge of astrocytes with VA, prior 24-h treatment with palmitic acid (PA), alpha-linolenic acid (ALA) or docosahexaenoic acid (DHA) has the effect on the FADS2 expression. Palmitic Acid 86-99 fatty acid desaturase 2 Homo sapiens 185-190 31751799-3 2020 Fatty acid desaturase 2 (FADS2) codes for a multifunctional enzyme that catalyzes Delta4-, Delta6- and Delta8-desaturation towards ten unsaturated fatty acids but only one saturate, palmitic acid, converting it to 16:1n-10; FADS2 is not active towards 14:0 or 18:0. Palmitic Acid 182-195 fatty acid desaturase 2 Homo sapiens 0-23 31751799-3 2020 Fatty acid desaturase 2 (FADS2) codes for a multifunctional enzyme that catalyzes Delta4-, Delta6- and Delta8-desaturation towards ten unsaturated fatty acids but only one saturate, palmitic acid, converting it to 16:1n-10; FADS2 is not active towards 14:0 or 18:0. Palmitic Acid 182-195 fatty acid desaturase 2 Homo sapiens 25-30 31751799-3 2020 Fatty acid desaturase 2 (FADS2) codes for a multifunctional enzyme that catalyzes Delta4-, Delta6- and Delta8-desaturation towards ten unsaturated fatty acids but only one saturate, palmitic acid, converting it to 16:1n-10; FADS2 is not active towards 14:0 or 18:0. Palmitic Acid 182-195 fatty acid desaturase 2 Homo sapiens 224-229 29750879-4 2018 The study examines whether challenge of astrocytes with VA, prior 24-h treatment with palmitic acid (PA), alpha-linolenic acid (ALA) or docosahexaenoic acid (DHA) has the effect on the FADS2 expression. Palmitic Acid 101-103 fatty acid desaturase 2 Homo sapiens 185-190 29750879-7 2018 Furthermore, similar changes were seen in VA-primed astrocytes with regard to delta6-desaturase protein levels following PA and DHA treatment. Palmitic Acid 121-123 fatty acid desaturase 2 Homo sapiens 78-95 26597785-0 2016 Palmitic acid (16:0) competes with omega-6 linoleic and omega-3 alpha-linolenic acids for FADS2 mediated Delta6-desaturation. Palmitic Acid 0-13 fatty acid desaturase 2 Homo sapiens 90-95 22119675-2 2011 These fatty acids belong to the n-10 series and the initial step involved in their synthesis is the desaturation of palmitic acid by the Delta6-desaturase to form sapienic acid. Palmitic Acid 116-129 fatty acid desaturase 2 Homo sapiens 143-154 14748719-6 2004 This Delta6-desaturase acts on a saturated fatty acid, palmitic acid (C(16:0)), leading to the newly characterized biosynthesis of hexadecenoic acid (C(16:1) n-10) or sapienate. Palmitic Acid 55-68 fatty acid desaturase 2 Homo sapiens 11-22