PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9488698-3	1998	Constitutive liver beta-oxidation of the long chain fatty acid, palmitic acid, was lower in the PPARalpha null mice as compared with wild type mice, indicating defective mitochondrial fatty acid catabolism.	Palmitic Acid	64-77	peroxisome proliferator activated receptor alpha	Mus musculus	96-105	
35222033-9	2022	Inhibition of miR-21 expression or Fenofibrate (PPARalpha agonist) administration prevented the decrease of PPARalpha in renal tubular epithelial cells under high glucose (HG) and high fat (Palmitic acid, PA) conditions, alleviating lipid metabolism disorders and reducing mitochondrial dynamics and inflammation.	Palmitic Acid	190-203	peroxisome proliferator activated receptor alpha	Mus musculus	108-117	
11246888-16	2001	PA-, SA-, and OA-stimulated binding activity was effectively diminished by immunoprecipitation of the nuclear proteins with anti-PPAR-alpha antibodies.	Palmitic Acid	0-2	peroxisome proliferator activated receptor alpha	Mus musculus	129-139	
34051224-10	2021	Inhibition of PPAR or CPT1alpha only partly reversed the IFN-gamma production of Apoc3TG-NK cells, but completely restored IFN-gamma secretion by palmitic acid-treated NK cells ex vivo, indicating that other factors contributed to the Apoc3TG-NK cell downregulation.	Palmitic Acid	146-159	peroxisome proliferator activated receptor alpha	Mus musculus	14-18	
30504232-7	2019	As expected, the corresponding lncRNAs were significantly elevated in AML12 cells treated with palmitic acid or the PPARalpha agonist, WY14643.	Palmitic Acid	95-108	peroxisome proliferator activated receptor alpha	Mus musculus	116-125	
25736301-7	2015	Exposure of primary hepatocytes to palmitic acid elevated the mRNA levels encoding DNA damage-inducible transcript 3, an indicator of ER stress, and FGF21 in a PPARalpha-independent manner, suggesting that lipid-induced ER stress can enhance hepatic FGF21 expression.	Palmitic Acid	35-48	peroxisome proliferator activated receptor alpha	Mus musculus	160-169	
19285478-3	2009	Diminished PPARalpha activation in L-FABP null hepatocytes was associated with lower uptake of common dietary LCFA (palmitic acid as well as its fluorescent derivative BODIPY FL C(16)), reduced level of total unesterified LCFA, and real-time redistribution of BODIPY FL C(16) from the central nucleoplasm to the nuclear envelope.	Palmitic Acid	116-129	peroxisome proliferator activated receptor alpha	Mus musculus	11-20	
30129056-10	2018	Luciferase reporter cell assay showed that nuciferine directly reversed palmitic acid-induced inhibition of PPARalpha transcriptional activity.	Palmitic Acid	72-85	peroxisome proliferator activated receptor alpha	Mus musculus	108-117	
21205704-10	2011	These changes were reproduced in cultured myocytes with the DGAT1 inhibitor, which also blocked the increase in mRNA levels of Ppar genes and their targets induced by palmitic acid.	Palmitic Acid	167-180	peroxisome proliferator activated receptor alpha	Mus musculus	127-131	
10801788-3	2000	The capacity for constitutive myocardial beta-oxidation of the medium and long chain fatty acids, octanoic acid and palmitic acid, was markedly reduced in the PPARalpha-null mice as compared with the wild-type mice, indicating that mitochondrial fatty acid catabolism is impaired in the absence of PPARalpha.	Palmitic Acid	116-129	peroxisome proliferator activated receptor alpha	Mus musculus	159-168