PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26991125-4 2016 We report that lipopolysaccharide/galactosamine-induced liver injury depends on hepatocyte-intrinsic TNF receptor 1 (p55, TNFR1). Galactosamine 34-47 tumor necrosis factor receptor superfamily, member 1a Mus musculus 117-120 31548168-11 2020 TNFR1 expression was reduced in d-galactosamine-treated mice (p<0.05) and cells incubated with tunicamycin for 12 and 24h (p<0.05). Galactosamine 32-47 tumor necrosis factor receptor superfamily, member 1a Mus musculus 0-5 26991125-4 2016 We report that lipopolysaccharide/galactosamine-induced liver injury depends on hepatocyte-intrinsic TNF receptor 1 (p55, TNFR1). Galactosamine 34-47 tumor necrosis factor receptor superfamily, member 1a Mus musculus 122-127 11753206-3 2001 In a series of recent studies, we have demonstrated that mortality and hepatic injury following lipopolysaccharide administration in D-galactosamine-sensitized mice is dependent upon secreted 17 kDa TNF-alpha acting primarily through the p55 TNF receptor. Galactosamine 133-148 tumor necrosis factor receptor superfamily, member 1a Mus musculus 238-241 15968724-16 2005 IOD level of TNFR1 changed significantly at 6, 9 and 12 h after GalN/LPS and GalN/TNFalpha administration. Galactosamine 64-68 tumor necrosis factor receptor superfamily, member 1a Mus musculus 13-18 15968724-17 2005 The expression of TNFR1 protein was significantly higher at 9 h after GalN/LPS and GalN/TNFalpha administration than that in control groups. Galactosamine 70-74 tumor necrosis factor receptor superfamily, member 1a Mus musculus 18-23 11753206-7 2001 The non-obese diabetic or NOD mouse is highly resistant to LPS-and D-galactosamine-induced lethality, and this appears to be secondary to a post-receptor defect in p55 TNF receptor signaling. Galactosamine 67-82 tumor necrosis factor receptor superfamily, member 1a Mus musculus 164-167 11753206-8 2001 The studies confirm an essential role for TNF-alpha and p55 TNF receptor signaling in the hepatocyte apoptosis and lethality associated with lipopolysaccharide and D-galactosamine administration. Galactosamine 164-179 tumor necrosis factor receptor superfamily, member 1a Mus musculus 56-59 10604572-9 1999 TNFR1 mRNA expression in the liver was upregulated within 3 h after GalN administration, and anti-TNFR1 antibody protected GalN-sensitized mice from hepatotoxic effects of TNF-alpha. Galactosamine 68-72 tumor necrosis factor receptor superfamily, member 1a Mus musculus 0-5 11086099-9 2000 The resistance to LPS- and TNF-alpha-mediated lethality and hepatic injury in D-galactosamine-sensitized NOD mice is apparently due to a post-TNFR binding defect, and independent of signaling pathways shared with Fas. Galactosamine 78-93 tumor necrosis factor receptor superfamily, member 1a Mus musculus 142-146 10801288-0 2000 LPS-induced liver injury in D-galactosamine-sensitized mice requires secreted TNF-alpha and the TNF-p55 receptor. Galactosamine 28-43 tumor necrosis factor receptor superfamily, member 1a Mus musculus 100-103 10801288-2 2000 The present study was undertaken to determine whether membrane-associated or secreted TNF-alpha signaling through the p55 or p75 receptor was responsible for survival and hepatic injury after lipopolysaccharide administration in D-galactosamine-sensitized mice. Galactosamine 229-244 tumor necrosis factor receptor superfamily, member 1a Mus musculus 118-121 10801288-7 2000 We conclude that survival and apoptotic liver injury in response to lipopolysaccharide and D-galactosamine are dependent exclusively on secreted TNF-alpha signaling through the p55 receptor. Galactosamine 91-106 tumor necrosis factor receptor superfamily, member 1a Mus musculus 177-180 10604572-9 1999 TNFR1 mRNA expression in the liver was upregulated within 3 h after GalN administration, and anti-TNFR1 antibody protected GalN-sensitized mice from hepatotoxic effects of TNF-alpha. Galactosamine 123-127 tumor necrosis factor receptor superfamily, member 1a Mus musculus 0-5 10604572-9 1999 TNFR1 mRNA expression in the liver was upregulated within 3 h after GalN administration, and anti-TNFR1 antibody protected GalN-sensitized mice from hepatotoxic effects of TNF-alpha. Galactosamine 123-127 tumor necrosis factor receptor superfamily, member 1a Mus musculus 98-103 10534346-2 1999 Injection of TNF or T-cell-activating agents (i.e., agonistic anti-CD3 antibody or staphylococcal enterotoxin B [SEB]) into galactosamine (GalN)-sensitized mice caused TNF/TNF-R1-dependent liver injury. Galactosamine 139-143 tumor necrosis factor receptor superfamily, member 1a Mus musculus 172-178 7760015-6 1995 Pretreatment of mice with p55 or IL-10 cDNA-liposome complexes improved survival (p < 0.01) to LPS-D-galactosamine. Galactosamine 102-117 tumor necrosis factor receptor superfamily, member 1a Mus musculus 26-29