PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12816762-6	2003	Studies from IFN-gamma-deficient mice indicate that IFN-gamma is the major cytokine responsible for activation and hyperexpression of STAT1 in LPS/D-galactosamine-induced hepatitis.	Galactosamine	149-162	interferon gamma	Mus musculus	13-22	
31637892-7	2019	RESULTS: SEB induced liver injury in D-galactosamine (D-gal)-sensitized mice, as demonstrated by increased serum levels of AST and ALT, elevated release of interferon-gamma (INF-gamma), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and IL-2, and promoted infiltrating immune cells into liver.	Galactosamine	37-52	interferon gamma	Mus musculus	156-172	
17353199-8	2007	d-Galactosamine-sensitized mice expressing defective TLR4 or lacking TLR4 expression acquired susceptibility to eLPS-driven toxemia upon IFNgamma priming, whereas double deficient mice did not.	Galactosamine	0-15	interferon gamma	Mus musculus	137-145	
15356173-4	2004	After injection of LPS/2-amino-2-deoxy-D-galactose (D-gal), CD137-/- mice had reduced serum cytokine levels and substantially impaired liver IFN-gamma and TNF-alpha mRNA levels.	Galactosamine	23-50	interferon gamma	Mus musculus	141-150	
12816762-6	2003	Studies from IFN-gamma-deficient mice indicate that IFN-gamma is the major cytokine responsible for activation and hyperexpression of STAT1 in LPS/D-galactosamine-induced hepatitis.	Galactosamine	149-162	interferon gamma	Mus musculus	52-61	
12649350-4	2003	Depletion of primary afferent nerve fibers by neonatal capsaicin treatment down-regulated circulating levels of the proinflammatory cytokines tumor necrosis factor-alpha (TNFalpha) and interferon-gamma (IFNgamma) and protected mice from GalN/LPS-induced liver injury.	Galactosamine	237-241	interferon gamma	Mus musculus	203-211	
12649350-10	2003	NK-1R blockade clearly inhibited GalN/LPS-induced production of TNFalpha and IFNgamma, whereas synthesis of the hepatoprotective cytokines IL-6 and IL-10 was increased.	Galactosamine	33-37	interferon gamma	Mus musculus	77-85	
10580578-0	1999	Interleukin-10 inhibits hepatic injury and tumor necrosis factor-alpha and interferon-gamma mRNA expression induced by staphylococcal enterotoxin B or lipopolysaccharide in galactosamine-sensitized mice.	Galactosamine	173-186	interferon gamma	Mus musculus	75-91	
10580578-1	1999	BACKGROUND/AIMS: Proinflammatory cytokines including tumor necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma) play a critical role in the pathogenesis of liver injury induced by lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) in D-galactosamine (GalN)-sensitized mice.	Galactosamine	260-275	interferon gamma	Mus musculus	97-124	
10580578-1	1999	BACKGROUND/AIMS: Proinflammatory cytokines including tumor necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma) play a critical role in the pathogenesis of liver injury induced by lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) in D-galactosamine (GalN)-sensitized mice.	Galactosamine	277-281	interferon gamma	Mus musculus	97-124	
8758269-4	1996	The serum total bilirubin (TBIL) and liver necrosis of mice increased more markedly by using of TNF alpha, IL-6 or IFN gamma separately with D-GAL (TBIL: 46.2 +/- 10.6 micromol/L, 44.6 +/- 12.9 micromol/L, 41.9 +/- 14.9 micromol/L), then by D-GAL alone (TBIL: 27 +/- 11 micromol/L) also the serum TBIL of mice and liver necrosis also increased after injection of IL-1, IL-6 with D-GAL and TNF alpha.	Galactosamine	141-146	interferon gamma	Mus musculus	115-124	
7890366-6	1995	In D-galactosamine-sensitized mice, SEB-induced weight loss but not hypoglycemia was more severe, resulting mostly in death within 24 h. Higher levels of biologically active TNF and IFN-gamma in serum were noted in these mice than in mice receiving SEB only.	Galactosamine	3-18	interferon gamma	Mus musculus	182-191	
7890366-14	1995	The data obtained with anti-IFN-gamma antibody clearly indicate that endogenous IFN-gamma is instrumental in bringing about hypoglycemia and body weight loss in mice exposed to SEB but also that hypoglycemia is not a crucial determinant of mortality in D-galactosamine-sensitized mice.	Galactosamine	253-268	interferon gamma	Mus musculus	80-89	
11828371-11	2002	Pretreatment with IFN-gamma rendered galactosamine-sensitized mice sensitive to challenge with LTA.	Galactosamine	37-50	interferon gamma	Mus musculus	18-27