PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12816762-6 2003 Studies from IFN-gamma-deficient mice indicate that IFN-gamma is the major cytokine responsible for activation and hyperexpression of STAT1 in LPS/D-galactosamine-induced hepatitis. Galactosamine 149-162 interferon gamma Mus musculus 13-22 31637892-7 2019 RESULTS: SEB induced liver injury in D-galactosamine (D-gal)-sensitized mice, as demonstrated by increased serum levels of AST and ALT, elevated release of interferon-gamma (INF-gamma), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and IL-2, and promoted infiltrating immune cells into liver. Galactosamine 37-52 interferon gamma Mus musculus 156-172 17353199-8 2007 d-Galactosamine-sensitized mice expressing defective TLR4 or lacking TLR4 expression acquired susceptibility to eLPS-driven toxemia upon IFNgamma priming, whereas double deficient mice did not. Galactosamine 0-15 interferon gamma Mus musculus 137-145 15356173-4 2004 After injection of LPS/2-amino-2-deoxy-D-galactose (D-gal), CD137-/- mice had reduced serum cytokine levels and substantially impaired liver IFN-gamma and TNF-alpha mRNA levels. Galactosamine 23-50 interferon gamma Mus musculus 141-150 12816762-6 2003 Studies from IFN-gamma-deficient mice indicate that IFN-gamma is the major cytokine responsible for activation and hyperexpression of STAT1 in LPS/D-galactosamine-induced hepatitis. Galactosamine 149-162 interferon gamma Mus musculus 52-61 12649350-4 2003 Depletion of primary afferent nerve fibers by neonatal capsaicin treatment down-regulated circulating levels of the proinflammatory cytokines tumor necrosis factor-alpha (TNFalpha) and interferon-gamma (IFNgamma) and protected mice from GalN/LPS-induced liver injury. Galactosamine 237-241 interferon gamma Mus musculus 203-211 12649350-10 2003 NK-1R blockade clearly inhibited GalN/LPS-induced production of TNFalpha and IFNgamma, whereas synthesis of the hepatoprotective cytokines IL-6 and IL-10 was increased. Galactosamine 33-37 interferon gamma Mus musculus 77-85 10580578-0 1999 Interleukin-10 inhibits hepatic injury and tumor necrosis factor-alpha and interferon-gamma mRNA expression induced by staphylococcal enterotoxin B or lipopolysaccharide in galactosamine-sensitized mice. Galactosamine 173-186 interferon gamma Mus musculus 75-91 10580578-1 1999 BACKGROUND/AIMS: Proinflammatory cytokines including tumor necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma) play a critical role in the pathogenesis of liver injury induced by lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) in D-galactosamine (GalN)-sensitized mice. Galactosamine 260-275 interferon gamma Mus musculus 97-124 10580578-1 1999 BACKGROUND/AIMS: Proinflammatory cytokines including tumor necrosis factor alpha (TNF-alpha) and interferon gamma (IFN-gamma) play a critical role in the pathogenesis of liver injury induced by lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) in D-galactosamine (GalN)-sensitized mice. Galactosamine 277-281 interferon gamma Mus musculus 97-124 8758269-4 1996 The serum total bilirubin (TBIL) and liver necrosis of mice increased more markedly by using of TNF alpha, IL-6 or IFN gamma separately with D-GAL (TBIL: 46.2 +/- 10.6 micromol/L, 44.6 +/- 12.9 micromol/L, 41.9 +/- 14.9 micromol/L), then by D-GAL alone (TBIL: 27 +/- 11 micromol/L) also the serum TBIL of mice and liver necrosis also increased after injection of IL-1, IL-6 with D-GAL and TNF alpha. Galactosamine 141-146 interferon gamma Mus musculus 115-124 7890366-6 1995 In D-galactosamine-sensitized mice, SEB-induced weight loss but not hypoglycemia was more severe, resulting mostly in death within 24 h. Higher levels of biologically active TNF and IFN-gamma in serum were noted in these mice than in mice receiving SEB only. Galactosamine 3-18 interferon gamma Mus musculus 182-191 7890366-14 1995 The data obtained with anti-IFN-gamma antibody clearly indicate that endogenous IFN-gamma is instrumental in bringing about hypoglycemia and body weight loss in mice exposed to SEB but also that hypoglycemia is not a crucial determinant of mortality in D-galactosamine-sensitized mice. Galactosamine 253-268 interferon gamma Mus musculus 80-89 11828371-11 2002 Pretreatment with IFN-gamma rendered galactosamine-sensitized mice sensitive to challenge with LTA. Galactosamine 37-50 interferon gamma Mus musculus 18-27