PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35202887-10 2022 We also noticed that liver TGFbetar1 deficiency alleviated LPS/GalN-induced apoptosis and ferroptosis by affecting the phosphorylation of glycogen synthase kinase 3beta and Nrf2, a key antioxidant factor, by up-regulating the levels of glutathione peroxidase 4, XCT, DHODH, and FSP1, and down-regulating transferrin receptor, cyclooxygenase 2, CHAC1, and POR expression. Galactosamine 63-67 prostaglandin-endoperoxide synthase 2 Mus musculus 326-342 30597306-5 2019 Moreover, AGD significantly inhibited LPS/GalN-induced inflammatory responses in mice with ALI by reducing not only the secretion of tumour necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6 but also the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Galactosamine 42-46 prostaglandin-endoperoxide synthase 2 Mus musculus 280-296 30597306-5 2019 Moreover, AGD significantly inhibited LPS/GalN-induced inflammatory responses in mice with ALI by reducing not only the secretion of tumour necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6 but also the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Galactosamine 42-46 prostaglandin-endoperoxide synthase 2 Mus musculus 298-303