PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11093734-2	2000	Pretreatment with TNF-alpha or interleukin-1beta (IL-1beta), which activated NF-kappaB in the liver, dramatically prevented TNF-alpha-induced liver-cell apoptosis in D-galactosamine (GalN)-sensitized mice, but not anti-Fas antibody-induced hepatotoxicity.	Galactosamine	183-187	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	77-86	
30597306-0	2019	Amygdalin attenuates acute liver injury induced by D-galactosamine and lipopolysaccharide by regulating the NLRP3, NF-kappaB and Nrf2/NQO1 signalling pathways.	Galactosamine	51-66	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	115-124	
34162160-0	2021	Lipopolysaccharide/D-galactosamine-induced acute liver injury could be attenuated by dopamine receptor agonist rotigotine via regulating NF-kappaB signaling pathway.	Galactosamine	19-34	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	137-146	
33566377-5	2021	Whereas GalN/LPS treatment-induced hepatic activation of NF-kappaB and JNK in wild-type and SphK2-/- mice, these signaling pathways were reduced in SphK1-/- mice.	Galactosamine	8-12	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	57-66	
30597306-8	2019	In summary, our investigations suggested that the ability of AGD to ameliorate LPS/GalN-induced ALI may involve the inhibition of the NLRP3 inflammasome and NF-kappaB signalling pathways and the upregulation of the Nrf2/NQO1 signalling pathway.	Galactosamine	83-87	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	157-166	
9035283-3	1997	In galactosamine-sensitized mice treated with 20 micrograms/kg murine TNF-alpha, DMSO moderately reduced hepatic NF-kappa B and decreased ICAM-1 mRNA formation and liver injury by 83%, but had no significant effect on hepatic neutrophil accumulation.	Galactosamine	3-16	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	113-123	
30597292-0	2019	Rosmarinic acid protects mice from lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting MAPKs/NF-kappaB and activating Nrf2/HO-1 signaling pathways.	Galactosamine	54-69	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	117-126	
29715757-0	2018	Madecassoside prevents acute liver failure in LPS/D-GalN-induced mice by inhibiting p38/NF-kappaB and activating Nrf2/HO-1 signaling.	Galactosamine	50-56	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	88-97	
30031824-0	2018	Daphnetin alleviates lipopolysaccharide/d-galactosamine-induced acute liver failure via the inhibition of NLRP3, MAPK and NF-kappaB, and the induction of autophagy.	Galactosamine	40-55	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	122-131	
28213269-0	2017	Protective effects of morin on lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting TLR4/NF-kappaB and activating Nrf2/HO-1 signaling pathways.	Galactosamine	50-65	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	112-121	
27711079-3	2016	Ablation of Sirt1 shows remarkable protection against GalN/LPS-induced liver injury, which is a result of enhanced NF-kappaB response because knockdown of RelA/p65 negates the protective effect of Sirt1 knockout.	Galactosamine	54-58	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	115-124	
27878238-8	2016	In addition, nobiletin suppressed LPS/GalN-induced phosphorylation and degradation of inhibitor of nuclear factor (NF)-kappaB (IkappaB)alpha, as well as NF-kappaB p65 translocation into the nucleus.	Galactosamine	38-42	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	99-125	
26494508-0	2015	Protective effects of sea buckthorn polysaccharide extracts against LPS/d-GalN-induced acute liver failure in mice via suppressing TLR4-NF-kappaB signaling.	Galactosamine	72-78	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	136-145	
26494508-12	2015	CONCLUSIONS: This study indicates that pretreatment with HRP protects against LPS/d-GalN-induced liver injury in mice via suppressing the TLR4-NF-kappaB signaling pathway.	Galactosamine	82-88	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	143-152	
21928088-15	2012	In addition, melittin prevented the activation of the transcription factor nuclear factor-kappa B (NF-kappaB) induced by GalN/LPS.	Galactosamine	121-125	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	75-97	
21928088-15	2012	In addition, melittin prevented the activation of the transcription factor nuclear factor-kappa B (NF-kappaB) induced by GalN/LPS.	Galactosamine	121-125	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	99-108	
16025521-6	2005	Here we describe that adenoviral expression of the NF-kappaB inhibitory protein ABIN-1, but not an IkappaBalpha superrepressor (IkappaBalpha(s)), completely prevents lethality in the TNF/D-(+)-galactosamine-induced model of liver failure.	Galactosamine	189-206	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	51-60	
19539484-2	2009	In this study, we attempted to use KG6 as a carrier of NFkappaB decoy oligonucleotide to the liver to treat hepatitis, induced by lipopolysaccharide and d-galactosamine.	Galactosamine	153-168	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	55-63	
12486082-0	2002	NFkappaB and caspase-3 activity in apoptotic hepatocytes of galactosamine-sensitized mice treated with TNFalpha.	Galactosamine	60-73	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	0-8