PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19675882-3	2009	The importance of NIS to diagnostic and research activities of Nuclear Medicine such as the radioiodine uptake, serum levels of TSH, TPO and TBG and thyroid diseases, especially cancer are described.	Nickel	18-21	thyroid peroxidase	Homo sapiens	133-136	
16052231-3	2006	Pre-incubation of the NIS/TPO-modified NSCLC cells in iodide followed by ionizing radiation generates bystander tumoricidal effects and potently enhances tumor cell killing.	Nickel	22-25	thyroid peroxidase	Homo sapiens	26-29	
11396709-7	2001	This is achieved by decreasing the intrathyroidal inorganic iodine concentration by down regulation of the sodium iodine symporter (NIS) and therefore permits the TPO-H202 system to resume normal activity.	Nickel	132-135	thyroid peroxidase	Homo sapiens	163-166	
23924466-7	2013	RESULTS: TPO ectodomain was recovered from the culture media as a soluble protein, and it was fused with a hexahistidine tag which allowed purification by nickel-affinity chromatography.	Nickel	155-161	thyroid peroxidase	Homo sapiens	9-12	
11571539-8	2001	In contrast, the combination of NIS and TPO gene transfer, with resulting TPO-mediated organification and intracellular retention of radioiodide, may lead to more effective tumor cell death.	Nickel	32-35	thyroid peroxidase	Homo sapiens	74-77	
11571539-9	2001	Thus, TPO could be used as a therapeutic strategy to enhance the NIS-based radioiodide concentrator gene therapy for locally advanced lung cancer.	Nickel	65-68	thyroid peroxidase	Homo sapiens	6-9