PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34889493-2 2022 Treatment of gem-difluoroalkenes with racemic benzyl electrophiles in the presence of a chiral nickel complex using B 2 pin 2 as a stoichiometric reductant allows the construction of a C(sp 2 )-C(sp 3 ) bond under mild conditions, affording a broad range of monofluoroalkenes bearing stereogenic allylic centers. Nickel 95-101 Sp2 transcription factor Homo sapiens 185-191 33625241-2 2021 Here, we describe the synthesis of a series of aryl and vinyl C-glycosides by stereoinvertive sp3-sp2 cross-coupling reactions of 2-deoxyglycosyl boronic acid derivatives with aryl or vinyl halide, mediated by a photoredox/nickel dual catalytic system. Nickel 223-229 Sp2 transcription factor Homo sapiens 98-101 34793680-2 2021 Herein, we report a new catalytic blueprint that merges the modularity of nickel catalysis for bond formation with the ability to enable a rather elusive 1,4-hydride shift at arene sp2 C-H sites, thus allowing access to ipso/ortho-difunctionalized arenes from readily available aryl halides under mild conditions and exquisite selectivity profile. Nickel 74-80 Sp2 transcription factor Homo sapiens 181-184 34163637-0 2021 Single-atom nickel terminating sp2 and sp3 nitride in polymeric carbon nitride for visible-light photocatalytic overall water splitting. Nickel 12-18 Sp2 transcription factor Homo sapiens 31-34 35175791-3 2022 This work leverages modern nickel-catalyzed electrochemical sp2-sp3 decarboxylative coupling reactions, enabled by silver nanoparticle-modified electrodes, to intuitively assemble terpene natural products and complex polyenes by using simple modular building blocks. Nickel 27-33 Sp2 transcription factor Homo sapiens 60-63 29787284-0 2018 Selective Synthesis of Aryl Nitriles and 3-Imino-1-oxoisoindolines via Nickel-Promoted C(sp2)-H Cyanations. Nickel 71-77 Sp2 transcription factor Homo sapiens 87-92 33300805-1 2020 Readily available aryldimethylsulfonium triflates react with zinc powder under nickel catalysis via the selective cleavage of the sp2-hybridized carbon-sulfur bond to produce salt-free arylzinc triflates under mild conditions. Nickel 79-85 Sp2 transcription factor Homo sapiens 130-133 32195579-0 2020 On The Nature of C(sp3)-C(sp2) Bond Formation in Nickel-Catalyzed Tertiary Radical Cross-Couplings: A Case Study of Ni/Photoredox Catalytic Cross-Coupling of Alkyl Radicals and Aryl Halides. Nickel 49-55 Sp2 transcription factor Homo sapiens 24-29 32017543-6 2020 Subsequently, the resulting remote carbon-centered radicals formed by C-C cleavage merge with the nickel catalytic cycle to create the challenging C(sp3)-C(sp2) bonds. Nickel 98-104 Sp2 transcription factor Homo sapiens 154-159 30673257-0 2019 One-Pot Electrochemical Nickel-Catalyzed Decarboxylative Sp2-Sp3 Cross-Coupling. Nickel 24-30 Sp2 transcription factor Homo sapiens 57-60 30673257-1 2019 A one-pot electrochemical nickel-catalyzed decarboxylative sp2-sp3 cross-coupling reaction has been developed using redox-active esters prepared in situ from alkyl carboxylates and N-hydroxyphthalimide tetramethyluronium hexafluorophosphate (PITU). Nickel 26-32 Sp2 transcription factor Homo sapiens 59-62 30184423-3 2018 Herein, we unlock a modular photochemical platform for forging C( sp3)-C( sp2) and C( sp3)-C( sp3) linkages from abundant alkane sp3 C-H bonds as functional handles using the synergy between nickel catalysts and simple, cheap and modular diaryl ketones. Nickel 191-197 Sp2 transcription factor Homo sapiens 74-77 31245805-0 2019 NIS-mediated oxidative arene C(sp2)-H amidation toward 3,4-dihydro-2(1H)-quinolinone, phenanthridone, and N-fused spirolactam derivatives. Nickel 0-3 Sp2 transcription factor Homo sapiens 29-34 31247793-1 2019 A nickel-catalyzed coupling of N-sulfonyl-1,2,3-triazole with various H-phosphine oxides for the construction of C(sp2)-P bonds is established. Nickel 2-8 Sp2 transcription factor Homo sapiens 113-118 31184197-1 2019 A nickel-catalyzed C(sp3)-C(sp2) Suzuki cross-coupling of arylboronic acids and (hetero)naphthyl alcohols has been developed. Nickel 2-8 Sp2 transcription factor Homo sapiens 26-31 30403224-1 2018 A bidentate directing group enabled regioselective arylation of C(sp2)-H bonds in aromatic carboxamides with aryl iodides under nickel-catalysis is reported, which provides the corresponding products in moderate to good yields. Nickel 128-134 Sp2 transcription factor Homo sapiens 64-69 28704055-0 2017 Electrochemical Nickel Catalysis for Sp2-Sp3 Cross-Electrophile Coupling Reactions of Unactivated Alkyl Halides. Nickel 16-22 Sp2 transcription factor Homo sapiens 37-40 29461813-0 2018 Ligand-Controlled Chemoselective C(acyl)-O Bond vs C(aryl)-C Bond Activation of Aromatic Esters in Nickel Catalyzed C(sp2)-C(sp3) Cross-Couplings. Nickel 99-105 Sp2 transcription factor Homo sapiens 116-121 28704055-1 2017 A constant-current electrochemical method for reducing catalytic nickel complexes in sp2-sp3 cross-electrophile coupling reactions has been developed. Nickel 65-71 Sp2 transcription factor Homo sapiens 85-88 28211695-0 2017 Synthesis of Benzoisoselenazolone Derivatives by Nickel-Catalyzed Dehydrogenative Direct Selenation of C(sp2)-H Bonds with Elemental Selenium in Air. Nickel 49-55 Sp2 transcription factor Homo sapiens 103-108 28447093-2 2017 The tosylate was activated by reduced VB12 to form alkyl cobalt(iii), which served as a good alkylating agent for aryl-nickel species, leading to C(sp3)-C(sp2) bond formation. Nickel 119-125 Sp2 transcription factor Homo sapiens 153-158 28287744-1 2017 A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. Nickel 2-8 Sp2 transcription factor Homo sapiens 135-140 27862759-3 2016 The nickel-catalytic system displays good chemoselectivity between the two C(sp2 )-halide coupling partners, thus demonstrating a mechanistic pathway distinct from other stepwise protocols. Nickel 4-10 Sp2 transcription factor Homo sapiens 75-80 28451200-3 2017 Described here is the use of primary and secondary ammonium alkylsilicates, which undergo facile C(sp3)-C(sp2) cross-coupling with borylated aryl bromide partners under photoredox/nickel dual catalysis conditions. Nickel 180-186 Sp2 transcription factor Homo sapiens 104-109 27815607-6 2016 Using the yellow-emitting Macrolampis sp2 firefly luciferase and site-directed mutagenesis, we show that the residues H310 and E354 constitute two critical sites for metal sensitivity that can be engineered to increase sensitivity to zinc, nickel, and mercury. Nickel 240-246 Sp2 transcription factor Homo sapiens 38-41 25650559-0 2015 Nickel-catalyzed enantioselective C-C bond formation through C(sp2)-O cleavage in aryl esters. Nickel 0-6 Sp2 transcription factor Homo sapiens 61-66 27709749-2 2016 Using these reagents, an efficient and high-throughput continuous flow process was developed to perform a dual iridium- and nickel-catalyzed C(sp2 )-C(sp3 ) coupling by circumventing solubility issues associated with potassium trifluoroborate salts. Nickel 124-130 Sp2 transcription factor Homo sapiens 141-146 21897993-0 2011 Nickel-catalyzed sp2 C-H bonds arylation of N-aromatic heterocycles with Grignard reagents at room temperature. Nickel 0-6 Sp2 transcription factor Homo sapiens 17-20 25532100-0 2015 Nickel catalyzed dealkoxylative C(sp2)-C(sp3) cross coupling reactions--stereospecific synthesis of allylsilanes from enol ethers. Nickel 0-6 Sp2 transcription factor Homo sapiens 32-37