PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27894244-7	2018	METHODS: In this work we have evaluated effects of umbelliferone and acetazolamide in a high resistant melanoma cell line (A375) over expressing CA IX.	7-hydroxycoumarin	51-64	carbonic anhydrase 9	Homo sapiens	145-150	
27894244-13	2018	Umbelliferone induced a more important pHi decrease than Acetalozamide from 7.3 to 7.08 and to 7.12 respectively, and a more important decrease in s-CA IX fraction showing a decrease in CA IX function.	7-hydroxycoumarin	0-13	carbonic anhydrase 9	Homo sapiens	149-154	
27894244-13	2018	Umbelliferone induced a more important pHi decrease than Acetalozamide from 7.3 to 7.08 and to 7.12 respectively, and a more important decrease in s-CA IX fraction showing a decrease in CA IX function.	7-hydroxycoumarin	0-13	carbonic anhydrase 9	Homo sapiens	186-191	
29197732-3	2018	By decorating the natural compound umbelliferone (1) we have identified a new series of coumarin-based compounds demonstrating high CA inhibitory effects with nanomolar affinity for hCA IX and hCA XII isoforms that were considered a target amenable to develop antitumor agents.	7-hydroxycoumarin	35-48	carbonic anhydrase 9	Homo sapiens	182-188