PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18642865-4 2008 Fluorogenic caspase-3 substrates 11 and 13 derived from umbelliferone and DAO, respectively, were prepared. 7-hydroxycoumarin 56-69 caspase 3 Homo sapiens 12-21 34258700-8 2021 BBR and UMB reduced the expression of pro-apoptotic protein Bax and apoptotic protein caspase-3 as well as increased the expression of anti-apoptotic protein Bcl-2. 7-hydroxycoumarin 8-11 caspase 3 Homo sapiens 86-95 26640551-0 2015 Single-cell microinjection assay indicates that 7-hydroxycoumarin induces rapid activation of caspase-3 in A549 cancer cells. 7-hydroxycoumarin 48-65 caspase 3 Homo sapiens 94-103 26640551-4 2015 A 24-h exposure to 1.85 mM 7-HC induced a 65% increase in C-3 activity, and a notable conversion of procaspase-3 to C-3, in addition to poly(ADP-ribose)polymerase cleavage. 7-hydroxycoumarin 27-31 caspase 3 Homo sapiens 58-61 26640551-4 2015 A 24-h exposure to 1.85 mM 7-HC induced a 65% increase in C-3 activity, and a notable conversion of procaspase-3 to C-3, in addition to poly(ADP-ribose)polymerase cleavage. 7-hydroxycoumarin 27-31 caspase 3 Homo sapiens 116-119