PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35278496-0	2022	Umbelliferone delays the progression of diabetic nephropathy by inhibiting ferroptosis through activation of the Nrf-2/HO-1 pathway.	7-hydroxycoumarin	0-13	nuclear factor, erythroid derived 2, like 2	Mus musculus	113-118	
34452623-0	2021	Anti-allergic activities of Umbelliferone against histamine- and Picryl chloride-induced ear edema by targeting Nrf2/iNOS signaling in mice.	7-hydroxycoumarin	28-41	nuclear factor, erythroid derived 2, like 2	Mus musculus	112-116	
34452623-13	2021	The UMB administration induced the Nrf2 expression, while attenuated the iNOS expression.	7-hydroxycoumarin	4-7	nuclear factor, erythroid derived 2, like 2	Mus musculus	35-39	
35278496-9	2022	We demonstrated that knockdown of Nrf2 blocked the inhibitory effect of Umbelliferone on ferroptosis in renal tubule cells induced by high glucose.	7-hydroxycoumarin	72-85	nuclear factor, erythroid derived 2, like 2	Mus musculus	34-38	
35278496-10	2022	CONCLUSION: These results suggest that Umbelliferone has a protective effect on DN, possibly by activating the Nrf2/HO-1 pathway, thus attenuating the level of high glucose-induced ferroptosis.	7-hydroxycoumarin	39-52	nuclear factor, erythroid derived 2, like 2	Mus musculus	111-115	
29967293-0	2018	Umbelliferone alleviates hepatic injury in diabetic db/db mice via inhibiting inflammatory response and activating Nrf2-mediated antioxidant.	7-hydroxycoumarin	0-13	nuclear factor, erythroid derived 2, like 2	Mus musculus	115-119	
32848758-0	2020	7-Hydroxycoumarin Attenuates Colistin-Induced Kidney Injury in Mice Through the Decreased Level of Histone Deacetylase 1 and the Activation of Nrf2 Signaling Pathway.	7-hydroxycoumarin	0-17	nuclear factor, erythroid derived 2, like 2	Mus musculus	143-147	
32848758-7	2020	7-HC treatment restored histone acetylation at the Nrf2 promoter region and hence promoted Nrf2 expression.	7-hydroxycoumarin	0-4	nuclear factor, erythroid derived 2, like 2	Mus musculus	51-55	
32848758-7	2020	7-HC treatment restored histone acetylation at the Nrf2 promoter region and hence promoted Nrf2 expression.	7-hydroxycoumarin	0-4	nuclear factor, erythroid derived 2, like 2	Mus musculus	91-95	
32848758-8	2020	These results suggested that 7-HC alleviates colistin-induced renal injury and this effect was achieved by enhancement of renal antioxidant capacity with the decreased level of HDAC1 and the activation of Nrf2 signaling pathway.	7-hydroxycoumarin	29-33	nuclear factor, erythroid derived 2, like 2	Mus musculus	205-209